Human complement factor 3 polymorphism determination by capillary electrophoresis of serum

Variability of complement factor 3 (C3) mobility in serum protein electrophoresis was investigated. We found that the migration time of C3 can be reproducibly determined (beween‐run CV=0.76%) using clinical capillary electrophoresis (CE) equipment (the Capillarys™ 2 system, Sebia). Moreover, we foun...

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Bibliographic Details
Published in:Electrophoresis 2012-02, Vol.33 (3), p.440-444
Main Authors: De Witte, Evy, Speeckaert, Marijn M., Van De Moortel, Lot, Lecocq, Elke, Delanghe, Joris R.
Format: Article
Language:English
Subjects:
Adult
Analysis of Variance
Blood Proteins - chemistry
Blotting, Western
Complement C3
Complement C3 - chemistry
Complement C3 - genetics
Electrophoresis, Capillary - methods
Female
Humans
Male
Middle Aged
Phenotype
Phenotyping
Polymorphism, Genetic
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Summary:Variability of complement factor 3 (C3) mobility in serum protein electrophoresis was investigated. We found that the migration time of C3 can be reproducibly determined (beween‐run CV=0.76%) using clinical capillary electrophoresis (CE) equipment (the Capillarys™ 2 system, Sebia). Moreover, we found a significant difference (p
ISSN:0173-0835
1522-2683
DOI:10.1002/elps.201100451