Analysis of bacterial surface interactions using microfluidic systems

Modern microbiological research has increasingly focused on the interactions between bacterial cells and the surfaces that they inhabit To this end, microfluidic devices have played a large role in enabling research of cellsurface interactions, especially surface attachment and biofilm formation. Th...

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Bibliographic Details
Published in:Science progress (1916) 2011-12, Vol.94 (4), p.431-450
Main Authors: MOSIER, AARON P., CADY, NATHANIEL C.
Format: Article
Language:English
Subjects:
Bacteria
Bacterial Adhesion
Biofilms
Cell adhesion
Cells
Fluid flow
Fluid shear
Microfluidic devices
Microfluidics
Microscopy
Physiological aspects
Reviews
Reynolds number
Semiconductors
Sensors
Surface reactions
Topography
Velocity
Viscosity
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Summary:Modern microbiological research has increasingly focused on the interactions between bacterial cells and the surfaces that they inhabit To this end, microfluidic devices have played a large role in enabling research of cellsurface interactions, especially surface attachment and biofilm formation. This review provides background on microfluidic devices and their use in biological systems, as well specific examples from current literature. Methods to observe and interrogate cells within microfluidic devices are described, as well as the analytical techniques that are used to collect these data.
ISSN:0036-8504
2047-7163
DOI:10.3184/003685011X13201828216868