Assessment of cerebral circulation in normal fetuses by three-dimensional power Doppler ultrasonography

• Published in: European journal of radiology 2012-03, Vol.81 (3), p.514-521
• Main Authors: Milani, Hérbene José Figuinha, de Sá Barreto, Enoch Quinderé, Araujo Júnior, Edward, Haratz, Karina Krajden, Rolo, Liliam Cristine, Nardozza, Luciano Marcondes Machado, Moron, Antonio Fernandes
• Format: Article
• Language: English
• Subjects: Adult; Cerebral circulation; Cerebrovascular Circulation; Cross-Sectional Studies; Female; Fetus; Fetus - blood supply; Gestational Age; Humans; Image Interpretation, Computer-Assisted; Imaging, Three-Dimensional - methods; Linear Models; Power Doppler; Pregnancy; Radiology; Statistics, Nonparametric; Three-dimensional ultrasound; Ultrasonography, Doppler - methods; Ultrasonography, Prenatal
• ISSN: 0720-048X; 1872-7727
• DOI: 10.1016/j.ejrad.2011.01.008

Abstract Objective: To assess the three-dimensional power Doppler ultrasonography (3D power Doppler) vascular indices in the middle cerebral artery (MCA), anterior cerebral artery (ACA) and posterior cerebral artery (PCA) territories. Methods: A cross-sectional study was carried out on 111 normal pregnancies between 26 and 34 weeks. The MCA, ACA and PCA territories closest to the transducer were scanned and volumes were calculated by using the VOCAL (Virtual Organ Computer-aided Analysis) program. The 3D power Doppler indices – vascularization index (VI), flow index (FI) and vascularization-flow index (VFI) were calculated. Scatter graphs, Pearson correlation coefficients ( r ) and linear regression models were used. Results: Only the FI-MCA ( r = 0.38 and p < 0.001), VFI-MCA ( r = 0.23 and p = 0.016) and FI-PCA ( r = 0.191 and p = 0.040) had a low correlation with gestational age. The other 3D power Doppler indices VI-MCA ( r = 0.153 and p = 0.150), VI-ACA ( r = 0.105 and p = 0.271), FI-ACA ( r = 0.154 and p = 0.106), VFI-ACA ( r = 0.134 and p = 0.161), VI-PCA ( r = 0.105 and p = 0.270) and VFI-PCA ( r = 0.126 and p = 0.180) showed no statistically significant correlation with gestational. Conclusion: It was observed a low correlation between gestational age and the FI-MCA, VFI-MCA and FI-PCA.