Is Laparoscopic Duodenojejunal Bypass with Sleeve an Effective Alternative to Roux En Y Gastric Bypass in Morbidly Obese Patients: Preliminary Results of a Randomized Trial

• Published in: Obesity surgery 2012-03, Vol.22 (3), p.422-426
• Main Authors: Praveen Raj, P., Kumaravel, R., Chandramaliteeswaran, C., Rajpandian, S., Palanivelu, C.
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Clinical Research; Clinical trials; Comorbidity; Comparative studies; Duodenum - surgery; Dyslipidemias - epidemiology; Dyslipidemias - surgery; Female; Gastric Bypass - methods; Gastrointestinal surgery; Humans; India; Jejunum - surgery; Laparoscopy - methods; Male; Medicine; Medicine & Public Health; Middle Aged; Obesity; Obesity, Morbid - epidemiology; Obesity, Morbid - surgery; Prospective Studies; Surgery; Surgical techniques; Treatment Outcome; Weight Loss; Young Adult
• ISSN: 0960-8923; 1708-0428
• DOI: 10.1007/s11695-011-0507-x

Background The incidence of obesity and related metabolic disorders in India and that of stomach carcinoma is one of the highest in the world. Hence, one requires a procedure that allows postoperative surveillance of the stomach with the best outcomes in terms of weight control and resolution of co-morbidities. Here, we compare one such procedure, duodenojejunal bypass with sleeve against the standard Roux-en Y gastric bypass. Methods Fifty-seven patients who were selected for a bypass procedure were randomized into two groups of laparoscopic duodenojejunal bypass with sleeve (DJB) and laparoscopic Roux en Y gastric bypass. The limb lengths were similar in both the groups, and the sleeve was done over a 36F bougie. Results The mean body mass index and percent excess weight loss at the end of 3, 6, and 12 months between the groups were not statistically significant. The operating times were higher in the DJB group. The rate of resolution of diabetes, hypertension, and dyslipidemias were also similar with no statistical significance. There was 100% resolution of dyslipidemias in both groups. There was one patient in the DJB group who presented with internal herniation 1 month post-op and was managed surgically. There was no mortality in both the groups. Conclusion Laparoscopic duodenojejunal with sleeve gastrectomy, a procedure which combines the principles and advantages of sleeve gastrectomy and foregut hypothesis, is a safe and effective alternative to gastric bypass in weight reduction and resolution of co-morbidities especially for Asian countries. But, long-term follow-up is required.