Ethics of clinical trials in dermatology

Abstract The ethics of clinical trials have been the subject of numerous previous publications and mandates that are used by institutional review boards on an everyday basis. The protection of human rights and the sanctity of informed consent are critical components of clinical research monitored by...

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Bibliographic Details
Published in:Clinics in dermatology 2012-03, Vol.30 (2), p.226-230
Main Authors: Slade, Karren L., APRN, Carreau, Nicole A, Heald, Peter, MD
Format: Article
Language:English
Subjects:
Adult
Aged
Clinical Trials as Topic - ethics
Conflict of Interest
Dermatology
Dermatology - ethics
Ethics, Medical
Female
Humans
Lymphoma, T-Cell, Cutaneous - therapy
Male
Middle Aged
Physician-Patient Relations - ethics
Rare Diseases - therapy
Skin Neoplasms - therapy
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Summary:Abstract The ethics of clinical trials have been the subject of numerous previous publications and mandates that are used by institutional review boards on an everyday basis. The protection of human rights and the sanctity of informed consent are critical components of clinical research monitored by human subjects investigation committees throughout our profession. In this contribution, the everyday conflicts of interest that can compromise clinical research in dermatology are presented in a case format. Of utmost importance, the primary interest of the investigating dermatologist should always be the patient at hand and those who could benefit from the research. Navigating the turbulence created by finances, academia, and corporate America is critical. By presenting several case scenarios within the relatively rare disease arena of cutaneous T-cell lymphoma, these conflicts can be appreciated. Consequently, understanding these influences in one disease setting permits generalizations to be applied to any dermatologic clinical research.
ISSN:0738-081X
1879-1131
DOI:10.1016/j.clindermatol.2011.06.012