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5S rRNA and ribosome
5S rRNA is an integral component of the ribosome of all living organisms. It is known that the ribosome without 5S rRNA is functionally inactive. However, the question about the specific role of this RNA in functioning of the translation apparatus is still open. This review presents a brief history...
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| Published in: | Biochemistry (Moscow) 2011-12, Vol.76 (13), p.1450-1464 |
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| Format: | Article |
| Language: | English |
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| cites | cdi_FETCH-LOGICAL-c470t-f8c07d99ef7e780b2e60de3cb1f84c7785260efa5e0ec7a90aacd88b7cf72d213 |
| container_end_page | 1464 |
| container_issue | 13 |
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| container_title | Biochemistry (Moscow) |
| container_volume | 76 |
| creator | Gongadze, G. M. |
| description | 5S rRNA is an integral component of the ribosome of all living organisms. It is known that the ribosome without 5S rRNA is functionally inactive. However, the question about the specific role of this RNA in functioning of the translation apparatus is still open. This review presents a brief history of the discovery of 5S rRNA and studies of its origin and localization in the ribosome. The previously expressed hypotheses about the role of this RNA in the functioning of the ribosome are discussed considering the unique location of 5S rRNA in the ribosome and its intermolecular contacts. Based on analysis of the current data on ribosome structure and its functional complexes, the role of 5S rRNA as an intermediary between ribosome functional domains is discussed. |
| doi_str_mv | 10.1134/S0006297911130062 |
| format | article |
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Based on analysis of the current data on ribosome structure and its functional complexes, the role of 5S rRNA as an intermediary between ribosome functional domains is discussed.</description><identifier>ISSN: 0006-2979</identifier><identifier>EISSN: 1608-3040</identifier><identifier>DOI: 10.1134/S0006297911130062</identifier><identifier>PMID: 22339598</identifier><language>eng</language><publisher>Dordrecht: SP MAIK Nauka/Interperiodica</publisher><subject>Bacteria ; Bacterial Proteins - chemistry ; Bacterial Proteins - metabolism ; Bacterial Proteins - physiology ; Base Sequence ; Biochemistry ; Biomedical and Life Sciences ; Biomedicine ; Bioorganic Chemistry ; Life Sciences ; Microbiology ; Molecular Sequence Data ; Nucleic Acid Conformation ; Organisms ; Protein Biosynthesis ; Protein Conformation ; Review ; Ribonucleic acid ; Ribosomal Proteins - chemistry ; Ribosomal Proteins - metabolism ; Ribosomal Proteins - physiology ; Ribosomes - chemistry ; Ribosomes - metabolism ; Ribosomes - physiology ; RNA ; RNA, Bacterial - chemistry ; RNA, Bacterial - metabolism ; RNA, Bacterial - physiology ; RNA, Ribosomal, 5S - chemistry ; RNA, Ribosomal, 5S - metabolism ; RNA, Ribosomal, 5S - physiology</subject><ispartof>Biochemistry (Moscow), 2011-12, Vol.76 (13), p.1450-1464</ispartof><rights>Pleiades Publishing, Ltd. 2011</rights><rights>COPYRIGHT 2011 Springer</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c470t-f8c07d99ef7e780b2e60de3cb1f84c7785260efa5e0ec7a90aacd88b7cf72d213</citedby><cites>FETCH-LOGICAL-c470t-f8c07d99ef7e780b2e60de3cb1f84c7785260efa5e0ec7a90aacd88b7cf72d213</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22339598$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gongadze, G. M.</creatorcontrib><title>5S rRNA and ribosome</title><title>Biochemistry (Moscow)</title><addtitle>Biochemistry Moscow</addtitle><addtitle>Biochemistry (Mosc)</addtitle><description>5S rRNA is an integral component of the ribosome of all living organisms. It is known that the ribosome without 5S rRNA is functionally inactive. However, the question about the specific role of this RNA in functioning of the translation apparatus is still open. This review presents a brief history of the discovery of 5S rRNA and studies of its origin and localization in the ribosome. The previously expressed hypotheses about the role of this RNA in the functioning of the ribosome are discussed considering the unique location of 5S rRNA in the ribosome and its intermolecular contacts. Based on analysis of the current data on ribosome structure and its functional complexes, the role of 5S rRNA as an intermediary between ribosome functional domains is discussed.</description><subject>Bacteria</subject><subject>Bacterial Proteins - chemistry</subject><subject>Bacterial Proteins - metabolism</subject><subject>Bacterial Proteins - physiology</subject><subject>Base Sequence</subject><subject>Biochemistry</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Bioorganic Chemistry</subject><subject>Life Sciences</subject><subject>Microbiology</subject><subject>Molecular Sequence Data</subject><subject>Nucleic Acid Conformation</subject><subject>Organisms</subject><subject>Protein Biosynthesis</subject><subject>Protein Conformation</subject><subject>Review</subject><subject>Ribonucleic acid</subject><subject>Ribosomal Proteins - chemistry</subject><subject>Ribosomal Proteins - metabolism</subject><subject>Ribosomal Proteins - physiology</subject><subject>Ribosomes - chemistry</subject><subject>Ribosomes - metabolism</subject><subject>Ribosomes - physiology</subject><subject>RNA</subject><subject>RNA, Bacterial - chemistry</subject><subject>RNA, Bacterial - metabolism</subject><subject>RNA, Bacterial - physiology</subject><subject>RNA, Ribosomal, 5S - chemistry</subject><subject>RNA, Ribosomal, 5S - metabolism</subject><subject>RNA, Ribosomal, 5S - physiology</subject><issn>0006-2979</issn><issn>1608-3040</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><recordid>eNp9kbtPwzAQxi0EouWxsbCgCgZYUs52HNtjVfGSEEgU5shxzlWqJgG7HfjvcdQC4ikP9vn7fZ_udIQcUhhSytPzCQBkTEtNY9k9N0ifZqASDilskn4nJ53eIzshzGLJQPNt0mOMcy206pMDMRn4h7vRwDTlwFdFG9oa98iWM_OA--t7lzxdXjyOr5Pb-6ub8eg2samEReKUBVlqjU6iVFAwzKBEbgvqVGqlVIJlgM4IBLTSaDDGlkoV0jrJSkb5Ljld5T779mWJYZHXVbA4n5sG22XINWMChOIdefYvSQGUYkpkIqLH39BZu_RNnCPmAQcpWRqhkxU0NXPMq8a1C29sl5mPeCoynSrFIzX8hYqnxLqybYOuiv9fDHRlsL4NwaPLn31VG_8aG8y7leU_VhY9R-t-l0WN5YfjfUcRYCsgRKmZov8c6O_UN0f_mmQ</recordid><startdate>20111201</startdate><enddate>20111201</enddate><creator>Gongadze, G. 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| ispartof | Biochemistry (Moscow), 2011-12, Vol.76 (13), p.1450-1464 |
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| source | Springer Nature:Jisc Collections:Springer Nature Read and Publish 2023-2025: Springer Reading List |
| subjects | Bacteria Bacterial Proteins - chemistry Bacterial Proteins - metabolism Bacterial Proteins - physiology Base Sequence Biochemistry Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Life Sciences Microbiology Molecular Sequence Data Nucleic Acid Conformation Organisms Protein Biosynthesis Protein Conformation Review Ribonucleic acid Ribosomal Proteins - chemistry Ribosomal Proteins - metabolism Ribosomal Proteins - physiology Ribosomes - chemistry Ribosomes - metabolism Ribosomes - physiology RNA RNA, Bacterial - chemistry RNA, Bacterial - metabolism RNA, Bacterial - physiology RNA, Ribosomal, 5S - chemistry RNA, Ribosomal, 5S - metabolism RNA, Ribosomal, 5S - physiology |
| title | 5S rRNA and ribosome |
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