Small-Cell Lung Cancer: Prognostic Factors and Changing Treatment Over 15 Years

Micro-Abstract Sixty-eight thousand six hundred eleven patients with small-cell lung cancer (SCLC) in the National Cancer Data Base were analyzed to describe demographic, treatment, and survival changes between 1992 and 2007. Despite changes in demographics and treatment, the median and 5-year survi...

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Bibliographic Details
Published in:Clinical lung cancer 2012-03, Vol.13 (2), p.115-122
Main Authors: Gaspar, Laurie E, McNamara, Erica J, Gay, E. Greer, Putnam, Joe B, Crawford, Jeffrey, Herbst, Roy S, Bonner, James A
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Combined Modality Therapy
Female
Hematology, Oncology and Palliative Medicine
Humans
Lung cancer
Lung Neoplasms - mortality
Lung Neoplasms - therapy
Male
Middle Aged
Neoplasm Staging
Prognosis
Prognostic factors
Pulmonary/Respiratory
Retrospective Studies
Small cell
Small Cell Lung Carcinoma - mortality
Small Cell Lung Carcinoma - therapy
Survival Rate
Time Factors
Treatment
Young Adult
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Summary:Micro-Abstract Sixty-eight thousand six hundred eleven patients with small-cell lung cancer (SCLC) in the National Cancer Data Base were analyzed to describe demographic, treatment, and survival changes between 1992 and 2007. Despite changes in demographics and treatment, the median and 5-year survival rates for patients with SCLC have not significantly improved over the past 15 years. Surgery was associated with improved survival in limited small-cell lung cancer (LSCLC). The benefit of chemotherapy and/or radiation therapy was dependent on stage.
ISSN:1525-7304
1938-0690
DOI:10.1016/j.cllc.2011.05.008