Candida glabrata Spinal Osteomyelitis

Abstract Invasive disease caused by Candida spp. is being appreciated with increased frequency especially associated with widespread use of immunosuppressive drug therapy. We report a case of spinal osteomyelitis and epidural abscess caused by Candida glabrata occurring in a patient who had been dia...

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Bibliographic Details
Published in:The American journal of the medical sciences 2011, Vol.341 (1), p.78-82
Main Authors: Dailey, Natalie J.M., MD, Young, Edward J., MD
Format: Article
Language:English
Subjects:
Abscesses
Aged
Amphotericin B
Antifungal Agents - therapeutic use
Bacterial arthritis and osteitis
Bacterial diseases
Biological and medical sciences
Candida
Candida glabrata
Candida glabrata - isolation & purification
Candidemia
Candidiasis - diagnosis
Candidiasis - drug therapy
Candidiasis - microbiology
Case reports
Disseminated infection
fluconazole
Fluconazole - therapeutic use
General aspects
Human bacterial diseases
Humans
Immunosuppressive agents
Infection
Infectious diseases
Internal Medicine
Male
Medical sciences
Osteomyelitis
Osteomyelitis - diagnostic imaging
Osteomyelitis - drug therapy
Osteomyelitis - microbiology
Radiography
Spinal cord
Spinal Diseases - diagnosis
Spinal Diseases - drug therapy
Spinal Diseases - microbiology
Spondylolisthesis
Torulopsis glabrata
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Description
Summary:Abstract Invasive disease caused by Candida spp. is being appreciated with increased frequency especially associated with widespread use of immunosuppressive drug therapy. We report a case of spinal osteomyelitis and epidural abscess caused by Candida glabrata occurring in a patient who had been diagnosed with candidemia 3 months before that patient was treated with fluconazole. The infection was successfully treated with amphotericin B, but the patient eventually required surgical intervention for spondylolisthesis with impingement on the cauda equina.
ISSN:0002-9629
1538-2990
DOI:10.1097/MAJ.0b013e3181f6c6ea