Retrospective audit of postictal generalized EEG suppression in telemetry

Summary Sudden unexpected death in epilepsy (SUDEP) has on rare occasions occurred during electroencephalography (EEG) telemetry, and in such cases postictal EEG suppression (PI EEG‐SUP) was frequently observed. More recently a retrospective case–control study reported this pattern as a risk factor...

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Bibliographic Details
Published in:Epilepsia (Copenhagen) 2012-02, Vol.53 (2), p.e21-e24
Main Authors: Semmelroch, Mira, Elwes, Robert D. C., Lozsadi, Dora A., Nashef, Lina
Format: Article
Language:English
Subjects:
Adolescent
Adult
Case-Control Studies
Child
Death, Sudden - etiology
EEG
Electroencephalography
Epilepsy
Epilepsy - complications
Epilepsy - physiopathology
Female
Humans
Male
Middle Aged
Mortality
Nursing
Oxygen
Postictal EEG suppression
Retrospective Studies
Risk factors
Seizures
Seizures - complications
Seizures - physiopathology
Sudden unexpected death in epilepsy
Telemetry
Tonic-clonic seizures
Young Adult
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Summary:Summary Sudden unexpected death in epilepsy (SUDEP) has on rare occasions occurred during electroencephalography (EEG) telemetry, and in such cases postictal EEG suppression (PI EEG‐SUP) was frequently observed. More recently a retrospective case–control study reported this pattern as a risk factor for SUDEP. We retrospectively audited frequency and electroclinical features of this pattern as well as immediate management following tonic–clonic seizures during telemetry. Forty‐eight patients with tonic–clonic seizures were identified from 470 consecutive EEG‐videotelemetry reports. Thirteen patients (27%) with PI EEG‐SUP (mean duration 38.1 s, range 6–69 s, median 38 s) were compared to 12 randomly selected controls. One seizure was analyzed per individual. Those with PI EEG‐SUP were significantly more likely to be motionless after the seizure and have simple nursing interventions performed (suction, oxygen administration, placed in recovery position, vital signs checked). This pattern is relatively common and requires further study as a potential marker for increased mortality in epilepsy.
ISSN:0013-9580
1528-1167
DOI:10.1111/j.1528-1167.2011.03296.x