Facile synthesis of magnetic one-dimensional polyaniline and its application in magnetic solid phase extraction for fluoroquinolones in honey samples

• Published in: Analytica chimica acta 2012-03, Vol.720, p.57-62
• Main Authors: Gao, Qiang, Zheng, Hao-Bo, Luo, Dan, Ding, Jun, Feng, Yu-Qi
• Format: Article
• Language: English
• Subjects: Analytical chemistry; Aniline Compounds - chemical synthesis; Aniline Compounds - chemistry; Chemistry; Chromatographic methods and physical methods associated with chromatography; Chromatography, High Pressure Liquid; Ethanol; Ethyl alcohol; Exact sciences and technology; Extraction; Fluoroquinolones; Fluoroquinolones - analysis; Fluoroquinolones - isolation & purification; High performance liquid chromatography; High performance liquid chromatography with fluorescence detection; Honey; Honey - analysis; Honey samples; Hydrogen-Ion Concentration; Magnetic one-dimensional polyaniline; Magnetic solid phase extraction; Magnetics; Magnetite Nanoparticles - chemistry; Magnetite Nanoparticles - ultrastructure; Other chromatographic methods; Oxidation-Reduction; Polyanilines; Solid Phase Extraction; Solid phases; Standard deviation
• ISSN: 0003-2670; 1873-4324
• DOI: 10.1016/j.aca.2011.12.067

By mixing magnetic nanoparticles (MNPs) and one-dimensional polyanilines (1D-PANIs) in a solvent, magnetic one-dimensional polyanilines (1D-PANIs/MNPs) were formed facilely due to the encapsulation of magnetic nanoparticles into the interconnected network of 1D-PANIs. The 1D-PANIs/MNPs have been demonstrated to be applicable for magnetic solid-phase extraction. [Display omitted] ► Magnetic 1D polyaniline (1D-PANIs/MNPs) was prepared by a simple co-mixing method. ► Efficacy of 1D-PANIs/MNPs for isolating four fluoroquinolones (FQs) from honey was tested. ► The optimized conditions were established for 1D-PANIs/MNPs-based magnetic solid-phase extraction (MSPE). ► π–π and hydrophobic interactions played a dominant role to the retention between the FQs and 1D-PANIs/MNPs. ► A simple, rapid, and effective MSPE-HPLC analysis method for FQs in honey samples was developed. In this work, we proposed a simple co-mixing method to fabricate magnetic one-dimensional polyaniline (denoted as 1D-PANIs/MNPs). One-dimensional polyanilines (1D-PANIs) and magnetic nanoparticles (MNPs) were prepared by chemical oxidation and solvothermal methods, respectively. When MNPs and 1D-PANIs (with mass ratio 4:1) were co-mixed and vortexed evenly in a solvent (e.g., ethanol, water, acetonitrile), they could assemble into 1D-PANIs/MNPs spontaneously and thus be magnetically separable. To testify the feasibility of 1D-PANIs/MNPs in sample preparation, it was applied as the sorbent for magnetic solid phase extraction (MSPE) of fluoroquinolones (FQs) in honey samples. Under optimized conditions, a rapid, convenient, and efficient method for the determination of four FQs in honey samples by 1D-PANIs/MNPs-based MSPE coupling with high performance liquid chromatography with fluorescence detection (HPLC-FLD) was established. The limits of detection (LODs) for four FQs ranged from 0.4 to 1.4ngg−1. The intra- and interday relative standard deviations (RSDs) were less than 17.6%. The recoveries of FQs for three spiked honey samples ranged from 86.3 to 121.3%, with RSDs of less than 16.3%.