Treatment of Gingival Recession Defects Using Coronally Advanced Flap With a Porcine Collagen Matrix Compared to Coronally Advanced Flap With Connective Tissue Graft: A Randomized Controlled Clinical Trial

Background: Connective tissue graft (CTG) plus coronally advanced flap (CAF) is the reference therapy for root coverage. The aim of the present study is to evaluate the use of a porcine collagen matrix (PCM) plus CAF as an alternative to CTG+CAF for the treatment of gingival recessions (REC), in a p...

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Bibliographic Details
Published in:Journal of periodontology (1970) 2012-03, Vol.83 (3), p.321-328
Main Authors: Cardaropoli, Daniele, Tamagnone, Lorenzo, Roffredo, Alessandro, Gaveglio, Lorena
Format: Article
Language:English
Subjects:
Adult
Animals
Biological and medical sciences
Collagen
Collagen - therapeutic use
Collagen Type I - therapeutic use
Collagen Type III - therapeutic use
connective tissue
Connective Tissue - transplantation
Dentistry
Female
Follow-Up Studies
Gingiva - pathology
Gingiva - transplantation
gingival recession
Gingival Recession - classification
Gingival Recession - surgery
guided tissue regeneration
Humans
Keratins
Male
Medical sciences
Membranes, Artificial
Middle Aged
Otorhinolaryngology. Stomatology
Periodontal Attachment Loss - surgery
Periodontal Pocket - surgery
Prospective Studies
Surgical Flaps
Swine
Tooth Root - pathology
Tooth Root - surgery
Young Adult
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Summary:Background: Connective tissue graft (CTG) plus coronally advanced flap (CAF) is the reference therapy for root coverage. The aim of the present study is to evaluate the use of a porcine collagen matrix (PCM) plus CAF as an alternative to CTG+CAF for the treatment of gingival recessions (REC), in a prospective randomized, controlled clinical trial. Methods: Eighteen adult patients participated in this study. The patients presented 22 single Miller's Class I or II REC, randomly assigned to the test (PCM+CAF) or control (CTG+CAF) group. REC, probing depth, clinical attachment level (CAL), and width of keratinized tissue (KG) were evaluated at 12 months. In addition, the gingival thickness (GT) was measured 1mm apical to the bottom of the sulcus. Results: At 12 months, mean REC was 0.23 mm for test sites and 0.09 mm for control sites (P
ISSN:0022-3492
1943-3670
DOI:10.1902/jop.2011.110215