Comparison of the effects of xylazine and romifidine administered perioperatively on the recovery of anesthetized horses

Comparison of the effects of xylazine and romifidine administered perioperatively on the recovery of anesthetized horses. The present study was designed to compare recoveries from anesthesia following the use of romifidine or xylazine in horses. In a prospective blind randomized clinical trial, 28 h...

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Bibliographic Details
Published in:Canadian veterinary journal 2011-09, Vol.52 (9), p.987-993
Main Authors: Bauquier, Sébastien H, Kona-Boun, Jean-Jacques
Format: Article
Language:fre
Subjects:
Anesthesia Recovery Period
Anesthesia, Intravenous - veterinary
Anesthetics, Combined - administration & dosage
Animals
Arthroscopy - veterinary
Blood Gas Analysis - veterinary
Blood Pressure - drug effects
Blood Pressure - physiology
Diazepam - administration & dosage
Double-Blind Method
Female
Horses - physiology
Horses - surgery
Imidazoles - administration & dosage
Ketamine - administration & dosage
Male
Perioperative Care - veterinary
Prospective Studies
Time Factors
Xylazine - administration & dosage
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Summary:Comparison of the effects of xylazine and romifidine administered perioperatively on the recovery of anesthetized horses. The present study was designed to compare recoveries from anesthesia following the use of romifidine or xylazine in horses. In a prospective blind randomized clinical trial, 28 horses, undergoing elective arthroscopy, were randomly allocated into 2 groups. The intravenous anesthesia protocol used in the xylazine group was: butorphanol [0.02 mg/kg body weight (BW)] and xylazine (0.5 to 0.7 mg/kg BW) for premedication, diazepam (0.1 mg/kg BW) and ketamine (2.2 mg/kg BW) for induction, isoflurane in oxygen for maintenance and xylazine (0.1 mg/kg BW) in recovery. The xylazine was replaced with romifidine 0.05 to 0.08 mg/kg BW (premedication) and 0.01 mg/kg BW (recovery) in the romifidine group. The quality of recovery was evaluated with a modified scoring system and the duration recorded. Wilcoxon Ranked Sum test (P < 0.05) was used for statistical analysis. The recovery quality scores and the durations of recovery were not statistically different between the 2 groups. In this study, romifidine and xylazine were equal in their effects on recovery qualities.(Translated by the authors).
ISSN:0008-5286