Technology behind commercial devices for blood glucose monitoring in diabetes management: A review

• Published in: Analytica chimica acta 2011-10, Vol.703 (2), p.124-136
• Main Authors: Vashist, Sandeep Kumar, Zheng, Dan, Al-Rubeaan, Khalid, Luong, John H.T., Sheu, Fwu-Shan
• Format: Article
• Language: English
• Subjects: Analytical chemistry; Blood; Blood Glucose - analysis; Blood glucose monitoring devices; Blood Glucose Self-Monitoring - instrumentation; Blood Glucose Self-Monitoring - methods; Blood Glucose Self-Monitoring - trends; Chemistry; Devices; Diabetes; Diabetes Mellitus - blood; Electrochemical methods; Electron mediators; Enzymes - chemistry; Enzymes - metabolism; Exact sciences and technology; Glucose; Glucose limiting membranes; Glucose strips; Humans; Interferences; Management; Mathematical analysis; Membranes, Artificial; Monitoring; Oxidation-Reduction; Uptakes
• ISSN: 0003-2670; 1873-4324
• DOI: 10.1016/j.aca.2011.07.024

The expanded views of Abbott's FreeStyle Navigator sensor chip for blood glucose monitoring [80]. [Display omitted] ► In this review article, we provide critical views on the technology behind commercial glucose sensor. ► We express opinion regarding the relative merits of designed sensors for monitoring serum glucose. ► We also comment as on the pros and cons of recently reported glucose biosensors in the literature. The blood glucose monitoring devices (BGMDs) are an integral part of diabetes management now-a-days. They have evolved tremendously within the last four decades in terms of miniaturization, rapid response, greater specificity, simplicity, minute sample requirement, painless sample uptake, sophisticated software and data management. This article aims to review the developments in the technologies behind commercial BGMD, especially those in the areas of chemistries, mediators and other components. The technology concerns, on-going developments and future trends in blood glucose monitoring (BGM) are also discussed.