Intergenerational change and familial aggregation of body mass index

The relationship between parental BMI and that of their adult offspring, when increased adiposity can become a clinical issue, is unknown. We investigated the intergenerational change in body mass index (BMI) distribution, and examined the sex-specific relationship between parental and adult offspri...

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Bibliographic Details
Published in:European journal of epidemiology 2012-01, Vol.27 (1), p.53-61
Main Authors: Johnson, Paul C. D., Logue, Jennifer, McConnachie, Alex, Abu-Rmeileh, Niveen M. E., Hart, Carole, Upton, Mark N., Lean, Mike, Sattar, Naveed, Watt, Graham
Format: Article
Language:English
Subjects:
Adult
Adults
Biological and medical sciences
Body mass
Body Mass Index
Cardiology
Children
Cohort Studies
Correlation coefficient
Daughters
Environment
Epidemiology
Family
Family medical history
Fathers
Female
Females
Gender
General aspects
Health Surveys
Heredity
Humans
Infectious Diseases
Linear Models
Male
Medical sciences
Medicine
Medicine & Public Health
Metabolic diseases
Middle Aged
Miscellaneous
Mothers
Obesity
Obesity - epidemiology
Obesity - etiology
Offspring
Oncology
Overweight
Overweight - epidemiology
Overweight - etiology
Parents
Population distributions
Public Health
Public health. Hygiene
Public health. Hygiene-occupational medicine
Regression Analysis
Scotland - epidemiology
Sex Factors
Sons
Surveys and Questionnaires
Women
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Summary:The relationship between parental BMI and that of their adult offspring, when increased adiposity can become a clinical issue, is unknown. We investigated the intergenerational change in body mass index (BMI) distribution, and examined the sex-specific relationship between parental and adult offspring BMI. Intergenerational change in the distribution of adjusted BMI in 1,443 complete families (both parents and at least one offspring) with 2,286 offspring (1,263 daughters and 1,023 sons) from the west of Scotland, UK, was investigated using quantile regression. Familial correlations were estimated from linear mixed effects regression models. The distribution of BMI showed little intergenerational change in the normal range (
ISSN:0393-2990
1573-7284
DOI:10.1007/s10654-011-9639-5