Polypectomy followed by adjuvant chemotherapy in a patient with sarcoma botryoides of the uterine cervix--case report and review of the literature

• Published in: Ginekologia polska 2011-11, Vol.82 (11), p.857-861
• Main Authors: Sobiczewski, Piotr, Dańska-Bidzińska, Anna, Miedzinska, Magdalena, Olszewski, Wojciech, Bidzinski, Mariusz
• Format: Article
• Language: English
• Subjects: Case reports; Cervix; Chemotherapy; Chemotherapy, Adjuvant; Female; Humans; Poland; Rhabdomyosarcoma, Embryonal - drug therapy; Rhabdomyosarcoma, Embryonal - pathology; Rhabdomyosarcoma, Embryonal - surgery; Sarcoma; Uterine Cervical Neoplasms - drug therapy; Uterine Cervical Neoplasms - pathology; Uterine Cervical Neoplasms - surgery; Young Adult
• ISSN: 0017-0011; 2543-6767

Embryonal rhabdomyosarcoma in a form of a polyp of the uterine cervix occurs mainly in young women in their second decade of life. The characteristic microscopic features are: the submucosal cambium layer and the presence of rhabdomyoblasts in the stroma. So far the treatment has not been well defined and ranges from conservative to radical surgery The presented case is a 22-year old woman with cervical polyp. Polypectomy with D&C was performed in 2005 and the microscopic examination revealed rhabdomyosarcoma botryoides. Detailed examination diagnosed stage 1a of the disease. The patient received 6 cycles of chemotherapy (Vincristine and Actinomycin). Conservative treatment may be considered in young women with favorable prognostic factors who wish to preserve their fertility Polypectomy followed by chemotherapy is a possible option for such patients.