Mapping for economic evaluation

Mapping provides a statistical algorithm that allows the estimation of utilities and consequently calculation of QALYs in clinical studies where preference-based measures are not implemented. Reviews of the mapping literature were utilized. Mapping requires similar populations between the estimation...

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Bibliographic Details
Published in:British medical bulletin 2012-03, Vol.101 (1), p.1-15
Main Authors: CHUANG, Ling-Hsiang, WHITEHEAD, Sarah J
Format: Article
Language:English
Subjects:
Algorithms
Biological and medical sciences
Cost-Benefit Analysis
General aspects
Health Status Indicators
Humans
Medical sciences
Miscellaneous
Models, Econometric
Outcome Assessment (Health Care) - methods
Public health. Hygiene
Public health. Hygiene-occupational medicine
Quality-Adjusted Life Years
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Summary:Mapping provides a statistical algorithm that allows the estimation of utilities and consequently calculation of QALYs in clinical studies where preference-based measures are not implemented. Reviews of the mapping literature were utilized. Mapping requires similar populations between the estimation and study data sets, with a high degree of overlap between the target and base measures being desirable. The National Institute for Health and Clinical Excellence recognizes mapping as a method to provide utility information. Areas of controversy Issues surrounding mapping include the descriptive system of the measure, the appropriate econometric method and model specification. There is a need for further research into the issue of over-prediction for severe health states and uncertainty around the estimated utility scores. Mapping continues to be an important area of research for economic evaluation, in particular validation of mapping functions.
ISSN:0007-1420
1471-8391
DOI:10.1093/bmb/ldr049