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Assessment of yeast cell wall as replacements for antibiotic growth promoters in broiler diets: effects on performance, intestinal histo‐morphology and humoral immune responses
The study compared the effects of an antibiotic growth promoter (AGP), yeast (Saccharomyces cerevisiae) and yeast cell wall (YCW) on performance, microbiology and histo‐morphology of the small intestine and humoral immune responses in Ross 308 broilers. The treatments (eight replicates/treatment, n ...
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| Published in: | Journal of animal physiology and animal nutrition 2012-04, Vol.96 (2), p.275-284 |
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| container_title | Journal of animal physiology and animal nutrition |
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| creator | Ghosh, T. K Haldar, S Bedford, M. R Muthusami, N Samanta, I |
| description | The study compared the effects of an antibiotic growth promoter (AGP), yeast (Saccharomyces cerevisiae) and yeast cell wall (YCW) on performance, microbiology and histo‐morphology of the small intestine and humoral immune responses in Ross 308 broilers. The treatments (eight replicates/treatment, n = 12/replicate) were negative control (NC, without AGP), positive control (PC, supplemented with bacitracin methylene disalicylate, 400 mg/kg), Y and YCW (supplemented with yeast and YCW, respectively, 1000 mg/kg). Live weight at 42 days improved (p = 0.086) in the PC, Y and YCW groups. Feed conversion ratio was better (p = 0.039) in the YCW group compared with the other groups. Antibiotic growth promoter in the PC group shortened the villi in duodenum (p = 0.044). Mucosal Escherichia coli number was higher in the PC group (p |
| doi_str_mv | 10.1111/j.1439-0396.2011.01155.x |
| format | article |
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K ; Haldar, S ; Bedford, M. R ; Muthusami, N ; Samanta, I</creator><creatorcontrib>Ghosh, T. K ; Haldar, S ; Bedford, M. R ; Muthusami, N ; Samanta, I</creatorcontrib><description>The study compared the effects of an antibiotic growth promoter (AGP), yeast (Saccharomyces cerevisiae) and yeast cell wall (YCW) on performance, microbiology and histo‐morphology of the small intestine and humoral immune responses in Ross 308 broilers. The treatments (eight replicates/treatment, n = 12/replicate) were negative control (NC, without AGP), positive control (PC, supplemented with bacitracin methylene disalicylate, 400 mg/kg), Y and YCW (supplemented with yeast and YCW, respectively, 1000 mg/kg). Live weight at 42 days improved (p = 0.086) in the PC, Y and YCW groups. Feed conversion ratio was better (p = 0.039) in the YCW group compared with the other groups. Antibiotic growth promoter in the PC group shortened the villi in duodenum (p = 0.044). Mucosal Escherichia coli number was higher in the PC group (p < 0.001), whereas in the digesta E. coli number was lower (p = 0.001) in the PC, Y and YCW groups in relation to the NC. Mucosal Salmonella populations increased (p = 0.0001) in the PC group, whereas in the digesta, all treatments reduced the Salmonella (p = 0.0001). Following oral challenge with Salmonella pullorum, YCW increased E. coli numbers on the mucosa (p < 0.001) whereas in the digesta the Y group had lower (p < 0.0001) number of E. coli. In the digesta, Salmonella count was lower in the YCW group compared with the other treatments (p < 0.01). Yeast cell wall ‐treated birds exhibited better (p < 0.05) humoral immune response against Newcastle disease which was far more persistent over time than in any other treatments. It was concluded that the yeast and the yeast cell wall may have effects identical to BMD on performance of broilers and thus may constitute an effective replacement strategy in the dietary regimens for broiler chickens.</description><identifier>ISSN: 0931-2439</identifier><identifier>EISSN: 1439-0396</identifier><identifier>DOI: 10.1111/j.1439-0396.2011.01155.x</identifier><identifier>PMID: 21535233</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Animal Feed - analysis ; Animal Nutritional Physiological Phenomena ; Animals ; Anti-Bacterial Agents - pharmacology ; antibiotic growth promoters ; Antibiotics ; Antibodies, Viral - blood ; Bacitracin ; body weight ; Bone mineral density ; broiler chickens ; Cell Wall - chemistry ; Cell walls ; Chickens - blood ; Chickens - growth & development ; Chickens - immunology ; diet ; Diet - veterinary ; Dietary Supplements ; Diets ; Duodenum ; Escherichia coli ; feed conversion ; growth promotion ; humoral immunity ; Immune response (humoral) ; immunity ; Immunity, Humoral ; intestinal histology ; Intestines - anatomy & histology ; Intestines - drug effects ; Mucosa ; Newcastle disease ; Newcastle Disease - immunology ; Newcastle Disease - prevention & control ; Poultry ; Promoters ; Saccharomyces cerevisiae ; Salmonella ; Salmonella enterica subsp. enterica serovar Pullorum ; Salmonella pullorum ; Small intestine ; villi ; Viral Vaccines - immunology ; yeast ; yeast cell wall ; Yeasts</subject><ispartof>Journal of animal physiology and animal nutrition, 2012-04, Vol.96 (2), p.275-284</ispartof><rights>2011 Blackwell Verlag GmbH</rights><rights>2011 Blackwell Verlag GmbH.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4915-8b10502d5cded80bc444df2c6d46da3df4dbd7c55bd0c08a8dcd3b4e35fd66843</citedby><cites>FETCH-LOGICAL-c4915-8b10502d5cded80bc444df2c6d46da3df4dbd7c55bd0c08a8dcd3b4e35fd66843</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21535233$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ghosh, T. K</creatorcontrib><creatorcontrib>Haldar, S</creatorcontrib><creatorcontrib>Bedford, M. R</creatorcontrib><creatorcontrib>Muthusami, N</creatorcontrib><creatorcontrib>Samanta, I</creatorcontrib><title>Assessment of yeast cell wall as replacements for antibiotic growth promoters in broiler diets: effects on performance, intestinal histo‐morphology and humoral immune responses</title><title>Journal of animal physiology and animal nutrition</title><addtitle>J Anim Physiol Anim Nutr (Berl)</addtitle><description>The study compared the effects of an antibiotic growth promoter (AGP), yeast (Saccharomyces cerevisiae) and yeast cell wall (YCW) on performance, microbiology and histo‐morphology of the small intestine and humoral immune responses in Ross 308 broilers. The treatments (eight replicates/treatment, n = 12/replicate) were negative control (NC, without AGP), positive control (PC, supplemented with bacitracin methylene disalicylate, 400 mg/kg), Y and YCW (supplemented with yeast and YCW, respectively, 1000 mg/kg). Live weight at 42 days improved (p = 0.086) in the PC, Y and YCW groups. Feed conversion ratio was better (p = 0.039) in the YCW group compared with the other groups. Antibiotic growth promoter in the PC group shortened the villi in duodenum (p = 0.044). Mucosal Escherichia coli number was higher in the PC group (p < 0.001), whereas in the digesta E. coli number was lower (p = 0.001) in the PC, Y and YCW groups in relation to the NC. Mucosal Salmonella populations increased (p = 0.0001) in the PC group, whereas in the digesta, all treatments reduced the Salmonella (p = 0.0001). Following oral challenge with Salmonella pullorum, YCW increased E. coli numbers on the mucosa (p < 0.001) whereas in the digesta the Y group had lower (p < 0.0001) number of E. coli. In the digesta, Salmonella count was lower in the YCW group compared with the other treatments (p < 0.01). Yeast cell wall ‐treated birds exhibited better (p < 0.05) humoral immune response against Newcastle disease which was far more persistent over time than in any other treatments. It was concluded that the yeast and the yeast cell wall may have effects identical to BMD on performance of broilers and thus may constitute an effective replacement strategy in the dietary regimens for broiler chickens.</description><subject>Animal Feed - analysis</subject><subject>Animal Nutritional Physiological Phenomena</subject><subject>Animals</subject><subject>Anti-Bacterial Agents - pharmacology</subject><subject>antibiotic growth promoters</subject><subject>Antibiotics</subject><subject>Antibodies, Viral - blood</subject><subject>Bacitracin</subject><subject>body weight</subject><subject>Bone mineral density</subject><subject>broiler chickens</subject><subject>Cell Wall - chemistry</subject><subject>Cell walls</subject><subject>Chickens - blood</subject><subject>Chickens - growth & development</subject><subject>Chickens - immunology</subject><subject>diet</subject><subject>Diet - veterinary</subject><subject>Dietary Supplements</subject><subject>Diets</subject><subject>Duodenum</subject><subject>Escherichia coli</subject><subject>feed conversion</subject><subject>growth promotion</subject><subject>humoral immunity</subject><subject>Immune response (humoral)</subject><subject>immunity</subject><subject>Immunity, Humoral</subject><subject>intestinal histology</subject><subject>Intestines - anatomy & histology</subject><subject>Intestines - drug effects</subject><subject>Mucosa</subject><subject>Newcastle disease</subject><subject>Newcastle Disease - immunology</subject><subject>Newcastle Disease - prevention & control</subject><subject>Poultry</subject><subject>Promoters</subject><subject>Saccharomyces cerevisiae</subject><subject>Salmonella</subject><subject>Salmonella enterica subsp. enterica serovar Pullorum</subject><subject>Salmonella pullorum</subject><subject>Small intestine</subject><subject>villi</subject><subject>Viral Vaccines - immunology</subject><subject>yeast</subject><subject>yeast cell wall</subject><subject>Yeasts</subject><issn>0931-2439</issn><issn>1439-0396</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNqNkstu1DAUhiMEoqXwCmCJBSzI4GsuSCyqEQyXqhRBVYmN5djOjKdJHOxEM7PjEXgWHokn4YQps2CBsOSL7O8_PvZ_kgQRPCPQnq9nhLMyxazMZhQTMoMuxGx7Kzk-HNxOjnHJSEph4yi5F-MaY5ILnN1NjigRTFDGjpMfpzHaGFvbDcjXaGdVHJC2TYM2CgYVUbB9o7SdiIhqH5DqBlc5PziNlsFvhhXqg2_9YENErkNV8K6xARlnh_gC2bq2GpS-Q70NoG9Vp-0zIAcbB9epBq1cHPzPb99bH_qVb_xyB3cYtBphA45d246dhTxi7ztI9n5yp1ZNtA9u5pPk8vWrz_M36dmHxdv56VmqeUlEWlQEC0yN0MaaAleac25qqjPDM6OYqbmpTK6FqAzWuFCF0YZV3DJRmywrODtJnuzjwvO-jpCsbF2cvkZ11o9RljQr8jxnAsin_yQJprgQglEC6OO_0LUfA_wCUILzsqS5yIAq9pQOPsZga9kH16qwg1ByqgC5lpPRcjJaThUgf1eA3IL04c0FY9VacxD-sRyAl3tgAzbt_juwfHdxPq1An-714JrdHvQqXMssZ7mQV-cL-RFffXm_mAt5AfyjPV8rL9UyuCgvP0FkjqGVlOfsF0VV3XE</recordid><startdate>201204</startdate><enddate>201204</enddate><creator>Ghosh, T. K</creator><creator>Haldar, S</creator><creator>Bedford, M. R</creator><creator>Muthusami, N</creator><creator>Samanta, I</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>FBQ</scope><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7T5</scope><scope>H94</scope><scope>M7N</scope><scope>7X8</scope></search><sort><creationdate>201204</creationdate><title>Assessment of yeast cell wall as replacements for antibiotic growth promoters in broiler diets: effects on performance, intestinal histo‐morphology and humoral immune responses</title><author>Ghosh, T. K ; Haldar, S ; Bedford, M. R ; Muthusami, N ; Samanta, I</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4915-8b10502d5cded80bc444df2c6d46da3df4dbd7c55bd0c08a8dcd3b4e35fd66843</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Animal Feed - analysis</topic><topic>Animal Nutritional Physiological Phenomena</topic><topic>Animals</topic><topic>Anti-Bacterial Agents - pharmacology</topic><topic>antibiotic growth promoters</topic><topic>Antibiotics</topic><topic>Antibodies, Viral - blood</topic><topic>Bacitracin</topic><topic>body weight</topic><topic>Bone mineral density</topic><topic>broiler chickens</topic><topic>Cell Wall - chemistry</topic><topic>Cell walls</topic><topic>Chickens - blood</topic><topic>Chickens - growth & development</topic><topic>Chickens - immunology</topic><topic>diet</topic><topic>Diet - veterinary</topic><topic>Dietary Supplements</topic><topic>Diets</topic><topic>Duodenum</topic><topic>Escherichia coli</topic><topic>feed conversion</topic><topic>growth promotion</topic><topic>humoral immunity</topic><topic>Immune response (humoral)</topic><topic>immunity</topic><topic>Immunity, Humoral</topic><topic>intestinal histology</topic><topic>Intestines - anatomy & histology</topic><topic>Intestines - drug effects</topic><topic>Mucosa</topic><topic>Newcastle disease</topic><topic>Newcastle Disease - immunology</topic><topic>Newcastle Disease - prevention & control</topic><topic>Poultry</topic><topic>Promoters</topic><topic>Saccharomyces cerevisiae</topic><topic>Salmonella</topic><topic>Salmonella enterica subsp. enterica serovar Pullorum</topic><topic>Salmonella pullorum</topic><topic>Small intestine</topic><topic>villi</topic><topic>Viral Vaccines - immunology</topic><topic>yeast</topic><topic>yeast cell wall</topic><topic>Yeasts</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ghosh, T. K</creatorcontrib><creatorcontrib>Haldar, S</creatorcontrib><creatorcontrib>Bedford, M. R</creatorcontrib><creatorcontrib>Muthusami, N</creatorcontrib><creatorcontrib>Samanta, I</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of animal physiology and animal nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ghosh, T. K</au><au>Haldar, S</au><au>Bedford, M. R</au><au>Muthusami, N</au><au>Samanta, I</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Assessment of yeast cell wall as replacements for antibiotic growth promoters in broiler diets: effects on performance, intestinal histo‐morphology and humoral immune responses</atitle><jtitle>Journal of animal physiology and animal nutrition</jtitle><addtitle>J Anim Physiol Anim Nutr (Berl)</addtitle><date>2012-04</date><risdate>2012</risdate><volume>96</volume><issue>2</issue><spage>275</spage><epage>284</epage><pages>275-284</pages><issn>0931-2439</issn><eissn>1439-0396</eissn><abstract>The study compared the effects of an antibiotic growth promoter (AGP), yeast (Saccharomyces cerevisiae) and yeast cell wall (YCW) on performance, microbiology and histo‐morphology of the small intestine and humoral immune responses in Ross 308 broilers. The treatments (eight replicates/treatment, n = 12/replicate) were negative control (NC, without AGP), positive control (PC, supplemented with bacitracin methylene disalicylate, 400 mg/kg), Y and YCW (supplemented with yeast and YCW, respectively, 1000 mg/kg). Live weight at 42 days improved (p = 0.086) in the PC, Y and YCW groups. Feed conversion ratio was better (p = 0.039) in the YCW group compared with the other groups. Antibiotic growth promoter in the PC group shortened the villi in duodenum (p = 0.044). Mucosal Escherichia coli number was higher in the PC group (p < 0.001), whereas in the digesta E. coli number was lower (p = 0.001) in the PC, Y and YCW groups in relation to the NC. Mucosal Salmonella populations increased (p = 0.0001) in the PC group, whereas in the digesta, all treatments reduced the Salmonella (p = 0.0001). Following oral challenge with Salmonella pullorum, YCW increased E. coli numbers on the mucosa (p < 0.001) whereas in the digesta the Y group had lower (p < 0.0001) number of E. coli. In the digesta, Salmonella count was lower in the YCW group compared with the other treatments (p < 0.01). Yeast cell wall ‐treated birds exhibited better (p < 0.05) humoral immune response against Newcastle disease which was far more persistent over time than in any other treatments. It was concluded that the yeast and the yeast cell wall may have effects identical to BMD on performance of broilers and thus may constitute an effective replacement strategy in the dietary regimens for broiler chickens.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>21535233</pmid><doi>10.1111/j.1439-0396.2011.01155.x</doi><tpages>10</tpages></addata></record> |
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| ispartof | Journal of animal physiology and animal nutrition, 2012-04, Vol.96 (2), p.275-284 |
| issn | 0931-2439 1439-0396 |
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| source | Wiley-Blackwell Read & Publish Collection |
| subjects | Animal Feed - analysis Animal Nutritional Physiological Phenomena Animals Anti-Bacterial Agents - pharmacology antibiotic growth promoters Antibiotics Antibodies, Viral - blood Bacitracin body weight Bone mineral density broiler chickens Cell Wall - chemistry Cell walls Chickens - blood Chickens - growth & development Chickens - immunology diet Diet - veterinary Dietary Supplements Diets Duodenum Escherichia coli feed conversion growth promotion humoral immunity Immune response (humoral) immunity Immunity, Humoral intestinal histology Intestines - anatomy & histology Intestines - drug effects Mucosa Newcastle disease Newcastle Disease - immunology Newcastle Disease - prevention & control Poultry Promoters Saccharomyces cerevisiae Salmonella Salmonella enterica subsp. enterica serovar Pullorum Salmonella pullorum Small intestine villi Viral Vaccines - immunology yeast yeast cell wall Yeasts |
| title | Assessment of yeast cell wall as replacements for antibiotic growth promoters in broiler diets: effects on performance, intestinal histo‐morphology and humoral immune responses |
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