Electrospun nanofibers for pharmaceutical and medical applications

Nanotechnology is one of the most promising and well-grown technologies of today with many potential pharmaceutical applications. Recent research applying nanotechnology in biomedicine suggests that the technology might solve problems in areas such as controlled release, various topical administrati...

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Bibliographic Details
Published in:Journal of drug delivery science and technology 2011, Vol.21 (6), p.451-468
Main Authors: Sridhar, R., Venugopal, J.R., Sundarrajan, S., Ravichandran, R., Ramalingam, B., Ramakrishna, S.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Drug delivery
Electrospinning
General pharmacology
Medical sciences
Nanofibers
Pharmaceutical technology. Pharmaceutical industry
Pharmacology. Drug treatments
Tissue engineering
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Summary:Nanotechnology is one of the most promising and well-grown technologies of today with many potential pharmaceutical applications. Recent research applying nanotechnology in biomedicine suggests that the technology might solve problems in areas such as controlled release, various topical administrations, gut absorption and targeted systemic delivery for tissue regeneration. Nanofibers mimic the porous topography of natural extracellular matrix (ECM), are advantageous for tissue regeneration and also for sustained release of encapsulated drug or growth factor. The present review elaborates specifically on electrospun polymeric nanofibrous scaffolds for tissue regeneration and controlled release of drugs as well as growth factors for therapeutic drug delivery.
ISSN:1773-2247
DOI:10.1016/S1773-2247(11)50075-9