Modular blue fluorescent RNA sensors for label-free detection of target molecules

A blue fluorescent RNA was applied to modular blue fluorescent RNA sensors, wherein a "recognition" event of the target molecule by the aptamer domain is transmitted through a "communication" module, to a "signaling" fluorescent RNA domain, which "lights up".

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Bibliographic Details
Published in:Molecular bioSystems 2010-09, Vol.6 (9), p.1569-1571
Main Authors: Furutani, Chika, Shinomiya, Kazuki, Aoyama, Yasuhiro, Yamada, Katsuhiro, Sando, Shinsuke
Format: Article
Language:English
Subjects:
Base Sequence
Biosensing Techniques - methods
Bisbenzimidazole - chemistry
Fluorescent Dyes - chemistry
Molecular Sequence Data
Nucleic Acid Conformation
RNA - chemistry
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Description
Summary:A blue fluorescent RNA was applied to modular blue fluorescent RNA sensors, wherein a "recognition" event of the target molecule by the aptamer domain is transmitted through a "communication" module, to a "signaling" fluorescent RNA domain, which "lights up".
ISSN:1742-206X
1742-2051
DOI:10.1039/c001230k