Module-assisted preparation of 64Cu with high specific activity

In this work the production of 64Cu via the 64Ni(p,n)64Cu reaction with optimized conditions for low current irradiation is presented. Different target setups and cleaning steps for lowering metal contaminations in the product were applied. 64Cu with high specific activities up to 1685GBq/μmol was p...

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Published in:Applied radiation and isotopes 2012-04, Vol.70 (4), p.602-608
Main Authors: Thieme, S., Walther, M., Pietzsch, H.-J., Henniger, J., Preusche, S., Mäding, P., Steinbach, J.
Format: Article
Language:English
Subjects:
64Cu
Automation
Copper Radioisotopes - chemistry
Cyclotron
Nickel
PET imaging
Radioactive Waste - prevention & control
Radioactivity
Radiopharmaceuticals - chemical synthesis
Radiotherapy
Targetry
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cited_by cdi_FETCH-LOGICAL-c2449-6b589a03052133106aff62b2d8935047b31baa8046f3941745af20d75568d9693
cites cdi_FETCH-LOGICAL-c2449-6b589a03052133106aff62b2d8935047b31baa8046f3941745af20d75568d9693
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container_start_page 602
container_title Applied radiation and isotopes
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creator Thieme, S.
Walther, M.
Pietzsch, H.-J.
Henniger, J.
Preusche, S.
Mäding, P.
Steinbach, J.
description In this work the production of 64Cu via the 64Ni(p,n)64Cu reaction with optimized conditions for low current irradiation is presented. Different target setups and cleaning steps for lowering metal contaminations in the product were applied. 64Cu with high specific activities up to 1685GBq/μmol was produced despite low overall activity (∼4.2GBq per run). The module processing leads to a highly reproducible, reliable product quality (
doi_str_mv 10.1016/j.apradiso.2012.01.019
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subjects 64Cu
Automation
Copper Radioisotopes - chemistry
Cyclotron
Nickel
PET imaging
Radioactive Waste - prevention & control
Radioactivity
Radiopharmaceuticals - chemical synthesis
Radiotherapy
Targetry
title Module-assisted preparation of 64Cu with high specific activity
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