Aromatic polyketide glycosides from an entomopathogenic fungus, Cordyceps indigotica

A new aromatic polyketide glycoside, indigotide A ( 1), was isolated from the culture broth of the entomopathogenic fungus, Cordyceps indigotica, along with known cyclic depsipeptides, destruxins A, A 2, B, B 2 and E ( 3– 7), and a polyketide, NG-393 ( 8). Repeated treatment of the C. indigotica cul...

Full description

Saved in:
Bibliographic Details
Published in:Tetrahedron letters 2012-01, Vol.53 (3), p.277-280
Main Authors: Asai, Teigo, Yamamoto, Takashi, Chung, Yu-Ming, Chang, Fang-Rong, Wu, Yang-Chang, Yamashita, Kouwa, Oshima, Yoshiteru
Format: Article
Language:English
Subjects:
Broths
Carbohydrates with 4, 5, 6, ... C atoms, dissacharides and oligosaccharides
Carbohydrates. Nucleosides and nucleotides
Chemistry
Culture
Deoxyribonucleic acid
DNA methyltransferase inhibitor
Entomopathogenic fungi
Epigenetics
Exact sciences and technology
Fungi
Glycosides
Heterocyclic compounds
Heterocyclic compounds with o, s, se, te hetero atom and condensed derivatives
Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings
Inhibitors
Organic chemistry
Peptides
Polyketides
Preparations and properties
Secondary metabolites
Tetrahedrons
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A new aromatic polyketide glycoside, indigotide A ( 1), was isolated from the culture broth of the entomopathogenic fungus, Cordyceps indigotica, along with known cyclic depsipeptides, destruxins A, A 2, B, B 2 and E ( 3– 7), and a polyketide, NG-393 ( 8). Repeated treatment of the C. indigotica culture broth with 5-azacytidine, a DNA methyltransferase inhibitor, led to the isolation of another new aromatic polyketide glycoside, indigotide B ( 2).
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2011.10.013