Diagnostic usefulness of the oedema-infarct ratio to differentiate acute from chronic myocardial damage using magnetic resonance imaging

• Published in: European radiology 2012-04, Vol.22 (4), p.789-795
• Main Authors: Yamada, Kiyoyasu, Isobe, Satoshi, Suzuki, Susumu, Kinoshita, Kousuke, Yokouchi, Kazuhiko, Iwata, Hirokazu, Ohshima, Satoru, Hirai, Makoto, Sawada, Ken, Murohara, Toyoaki
• Format: Article
• Language: English
• Subjects: Acute Disease; Adult; Aged; Aged, 80 and over; Angioplasty; Cardiac; Cardiology; Chronic Disease; Diagnosis, Differential; Diagnostic Radiology; Edema; Edema - complications; Edema - diagnosis; Electrocardiography; Female; Heart attacks; Humans; Image Enhancement - methods; Image Interpretation, Computer-Assisted - methods; Imaging; Internal Medicine; Interventional Radiology; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Male; Medicine; Medicine & Public Health; Middle Aged; Myocardial Infarction - complications; Myocardial Infarction - diagnosis; Neuroradiology; Radiology; Reproducibility of Results; Sensitivity and Specificity; Ultrasound; Veins & arteries
• ISSN: 0938-7994; 1432-1084
• DOI: 10.1007/s00330-011-2327-8

Objectives To differentiate acute from chronic damage to the myocardium in patients with myocardial infarction (MI) using DE and T2w MR. Methods Short-axis T2w and DE MR images were acquired twice after the onset of MI in 36 patients who successfully underwent emergency coronary revascularisation. The areas of infarct and oedema were measured. The oedema-infarct ratio (O/I) of the left ventricular area was calculated by dividing the oedema by the infarct area. Results The oedema size on T2w MR was significantly larger than the infarct size on DE MR in the acute phase. Both the oedema size on T2w MR and the infarct size on DE MR in the acute phase were significantly larger than those in the chronic phase. The O/I was significantly greater in the acute phase compared with that in the chronic phase ( P