Soluble Human Leukocyte Antigen-G Expression in Patients with Ductal and Lobular Breast Malignancy

Human leukocyte antigen-G (HLA-G) has been closely associated with diagnosis and prognosis in many types of human cancer. The current study aims to investigate soluble (s) HLA-G expression in patients with breast malignancy. sHLA-G plasma expression was determined in 120 patients with breast cancer...

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Bibliographic Details
Published in:Anticancer research 2012-03, Vol.32 (3), p.1021-1026
Main Authors: PROVATOPOULOU, Xeni, KALOGERA, Eleni, SAGKRIOTIS, Alexandros, ZAGOURI, Flora, NONNI, Aphroditi, ZOGRAFOS, George C, GOUNARIS, Antonia
Format: Article
Language:English
Subjects:
Adult
Aged
Biological and medical sciences
Breast Neoplasms - genetics
Breast Neoplasms - immunology
Carcinoma, Ductal, Breast - genetics
Carcinoma, Ductal, Breast - immunology
Carcinoma, Lobular - genetics
Carcinoma, Lobular - immunology
Case-Control Studies
Enzyme-Linked Immunosorbent Assay
Female
Gynecology. Andrology. Obstetrics
HLA-G Antigens - blood
HLA-G Antigens - genetics
Humans
Mammary gland diseases
Medical sciences
Middle Aged
Tumors
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Summary:Human leukocyte antigen-G (HLA-G) has been closely associated with diagnosis and prognosis in many types of human cancer. The current study aims to investigate soluble (s) HLA-G expression in patients with breast malignancy. sHLA-G plasma expression was determined in 120 patients with breast cancer and 40 healthy controls using enzyme-linked immunosorbent assay. Plasma sHLA-G levels were significantly higher in breast cancer patients compared to healthy controls (p
ISSN:0250-7005
1791-7530