Atypical presentation of pediatric mixed germ cell tumors in the sellar-suprasellar region

Intracranial germ cell tumors constitute a unique group of tumors, more often reported from the Asian region. Amongst them, the non-germinomatous variety occurs with a lesser frequency than the germinomatous variety. We report two children with mixed germ cell tumors with unusual clinical presentati...

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Bibliographic Details
Published in:Neurology India 2012-01, Vol.60 (1), p.90-93
Main Authors: Furtado, Sunil V, Thakar, Sumit, Ghosal, Nandita, Hegde, Alangar S
Format: Article
Language:English
Subjects:
Adolescent
Care and treatment
Case studies
Child
CT imaging
Diabetes Insipidus, Neurogenic - etiology
Diagnosis
Female
Germ cell tumors
Germinoma - complications
Germinoma - diagnostic imaging
Germinoma - metabolism
Germinoma - pathology
Health aspects
Hormones - metabolism
Humans
Magnetic Resonance Imaging
Male
Neoplasms, Germ Cell and Embryonal - complications
Neoplasms, Germ Cell and Embryonal - diagnostic imaging
Neoplasms, Germ Cell and Embryonal - metabolism
Neoplasms, Germ Cell and Embryonal - pathology
Patient outcomes
Pituitary Apoplexy - etiology
Risk factors
Sella Turcica - diagnostic imaging
Sella Turcica - pathology
Tomography, X-Ray Computed
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Summary:Intracranial germ cell tumors constitute a unique group of tumors, more often reported from the Asian region. Amongst them, the non-germinomatous variety occurs with a lesser frequency than the germinomatous variety. We report two children with mixed germ cell tumors with unusual clinical presentations: Central diabetes insipidus and recent-onset oculomotor palsy mimicking pituitary apoplexy. Unlike in adults, suprasellar lesions with a pituitary apoplexy-like picture in the pediatric age group may suggest a possibility of a mixed germ cell tumor.
ISSN:0028-3886
1998-4022
DOI:10.4103/0028-3886.93611