Loading…
Recovery of consciousness following acute symptomatic seizures due to central nervous system infections in children
Aim The aim of this study was to assess whether acute symptomatic epileptic seizures associated with central nervous system infections (ASinf) have a different ictal and postictal course to seizures of other aetiologies. Method A case note analysis of 81 children (47 males; 34 females; age range 1...
Saved in:
| Published in: | Developmental medicine and child neurology 2012-04, Vol.54 (4), p.324-327 |
|---|---|
| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c5477-41446ea8967a30af041984700659e48ac898ab991d2bd5d396ed70a1bd43d3ba3 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c5477-41446ea8967a30af041984700659e48ac898ab991d2bd5d396ed70a1bd43d3ba3 |
| container_end_page | 327 |
| container_issue | 4 |
| container_start_page | 324 |
| container_title | Developmental medicine and child neurology |
| container_volume | 54 |
| creator | KING, ELEANOR J FERRIE, COLIN D LIVINGSTON, JOHN H TAYLOR, JOHN C |
| description | Aim The aim of this study was to assess whether acute symptomatic epileptic seizures associated with central nervous system infections (ASinf) have a different ictal and postictal course to seizures of other aetiologies.
Method A case note analysis of 81 children (47 males; 34 females; age range 1mo–15y 6mo; median age 12mo) with central nervous system infections was undertaken. Seizure type, duration, aetiology, and timing were recorded. Recovery time to full consciousness in those not intubated was determined. Intubation rates and recovery times were compared with those from previous studies.
Results Of the 81 children, 40 (49.4%) had one or more ASinf. The different aetiologies were bacterial meningitis, aseptic meningitis, abscess/empyema, encephalitis, and postoperative infection. Twenty‐two had status epilepticus. The intubation rate in children with ASinf was higher than that in children with seizures of other aetiologies (21/40 [52.5%] vs 4/124 [3.23%]; p < 0.0001). Median postictal recovery time was 4.33 hours (0–207h). Children with ASinf took 4.3 (p |
| doi_str_mv | 10.1111/j.1469-8749.2012.04227.x |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_927834246</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>927834246</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5477-41446ea8967a30af041984700659e48ac898ab991d2bd5d396ed70a1bd43d3ba3</originalsourceid><addsrcrecordid>eNqNkM1u1DAURi0EokPhFZB3rBL8FzveIKEptJWGIkERS8txbsBDEg920s7w9HWYMmu88ZXu9x1bByFMSUnzebstqZC6qJXQJSOUlUQwpsr9E7Q6LZ6iFcmrgkrGztCLlLaEEC4r8RydMcYrxnS9QukLuHAH8YBDh10Yk_NhTiOkhLvQ9-Hejz-wdfMEOB2G3RQGO3mHE_g_c4SE2xnwFLCDcYq2xyPEu9zP2TTBgP3YgZt8xuYRu5--byOML9GzzvYJXj3e5-jbxw-366ti8_nyev1-U7hKKFUIKoQEW2upLCe2I4LqWihCZKVB1NbVuraN1rRlTVu1XEtoFbG0aQVveWP5OXpz5O5i-D1Dmszgk4O-tyPkTxrNVM0FEzIn62PSxZBShM7soh9sPBhKzGLcbM0i1ixizWLc_DVu9rn6-vGRuRmgPRX_Kc6Bd8fAve_h8N9gc_FpfbOMGVAcAT473Z8ANv4yUnFVme83l-aWb9T66oKbr_wBBUyhSA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>927834246</pqid></control><display><type>article</type><title>Recovery of consciousness following acute symptomatic seizures due to central nervous system infections in children</title><source>Wiley-Blackwell Read & Publish Collection</source><creator>KING, ELEANOR J ; FERRIE, COLIN D ; LIVINGSTON, JOHN H ; TAYLOR, JOHN C</creator><creatorcontrib>KING, ELEANOR J ; FERRIE, COLIN D ; LIVINGSTON, JOHN H ; TAYLOR, JOHN C</creatorcontrib><description>Aim The aim of this study was to assess whether acute symptomatic epileptic seizures associated with central nervous system infections (ASinf) have a different ictal and postictal course to seizures of other aetiologies.
Method A case note analysis of 81 children (47 males; 34 females; age range 1mo–15y 6mo; median age 12mo) with central nervous system infections was undertaken. Seizure type, duration, aetiology, and timing were recorded. Recovery time to full consciousness in those not intubated was determined. Intubation rates and recovery times were compared with those from previous studies.
Results Of the 81 children, 40 (49.4%) had one or more ASinf. The different aetiologies were bacterial meningitis, aseptic meningitis, abscess/empyema, encephalitis, and postoperative infection. Twenty‐two had status epilepticus. The intubation rate in children with ASinf was higher than that in children with seizures of other aetiologies (21/40 [52.5%] vs 4/124 [3.23%]; p < 0.0001). Median postictal recovery time was 4.33 hours (0–207h). Children with ASinf took 4.3 (p<0.01), 3.0 (p=0.004), and 8.8 (p<0.001) times longer to recover than children who had seizures from all causes, remote symptomatic seizures, and febrile seizures respectively.
Interpretation ASinf in children are often longer, more likely to be associated with status epilepticus, more likely to necessitate intubation, and take longer to recover from than seizures of other aetiologies. This may help in the early diagnosis of central nervous system infection in children presenting with seizures.</description><identifier>ISSN: 0012-1622</identifier><identifier>EISSN: 1469-8749</identifier><identifier>DOI: 10.1111/j.1469-8749.2012.04227.x</identifier><identifier>PMID: 22352298</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Acute Disease ; Adolescent ; Central Nervous System Infections - complications ; Central Nervous System Infections - etiology ; Child ; Child, Preschool ; Consciousness - physiology ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Meningitis, Aseptic - complications ; Meningitis, Bacterial - complications ; Postoperative Complications - physiopathology ; Recovery of Function ; Seizures - classification ; Seizures - etiology ; Seizures - parasitology ; Seizures - virology ; Time Factors</subject><ispartof>Developmental medicine and child neurology, 2012-04, Vol.54 (4), p.324-327</ispartof><rights>The Authors. Developmental Medicine & Child Neurology © 2012 Mac Keith Press</rights><rights>The Authors. Developmental Medicine & Child Neurology © 2012 Mac Keith Press.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5477-41446ea8967a30af041984700659e48ac898ab991d2bd5d396ed70a1bd43d3ba3</citedby><cites>FETCH-LOGICAL-c5477-41446ea8967a30af041984700659e48ac898ab991d2bd5d396ed70a1bd43d3ba3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22352298$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>KING, ELEANOR J</creatorcontrib><creatorcontrib>FERRIE, COLIN D</creatorcontrib><creatorcontrib>LIVINGSTON, JOHN H</creatorcontrib><creatorcontrib>TAYLOR, JOHN C</creatorcontrib><title>Recovery of consciousness following acute symptomatic seizures due to central nervous system infections in children</title><title>Developmental medicine and child neurology</title><addtitle>Dev Med Child Neurol</addtitle><description>Aim The aim of this study was to assess whether acute symptomatic epileptic seizures associated with central nervous system infections (ASinf) have a different ictal and postictal course to seizures of other aetiologies.
Method A case note analysis of 81 children (47 males; 34 females; age range 1mo–15y 6mo; median age 12mo) with central nervous system infections was undertaken. Seizure type, duration, aetiology, and timing were recorded. Recovery time to full consciousness in those not intubated was determined. Intubation rates and recovery times were compared with those from previous studies.
Results Of the 81 children, 40 (49.4%) had one or more ASinf. The different aetiologies were bacterial meningitis, aseptic meningitis, abscess/empyema, encephalitis, and postoperative infection. Twenty‐two had status epilepticus. The intubation rate in children with ASinf was higher than that in children with seizures of other aetiologies (21/40 [52.5%] vs 4/124 [3.23%]; p < 0.0001). Median postictal recovery time was 4.33 hours (0–207h). Children with ASinf took 4.3 (p<0.01), 3.0 (p=0.004), and 8.8 (p<0.001) times longer to recover than children who had seizures from all causes, remote symptomatic seizures, and febrile seizures respectively.
Interpretation ASinf in children are often longer, more likely to be associated with status epilepticus, more likely to necessitate intubation, and take longer to recover from than seizures of other aetiologies. This may help in the early diagnosis of central nervous system infection in children presenting with seizures.</description><subject>Acute Disease</subject><subject>Adolescent</subject><subject>Central Nervous System Infections - complications</subject><subject>Central Nervous System Infections - etiology</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Consciousness - physiology</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Meningitis, Aseptic - complications</subject><subject>Meningitis, Bacterial - complications</subject><subject>Postoperative Complications - physiopathology</subject><subject>Recovery of Function</subject><subject>Seizures - classification</subject><subject>Seizures - etiology</subject><subject>Seizures - parasitology</subject><subject>Seizures - virology</subject><subject>Time Factors</subject><issn>0012-1622</issn><issn>1469-8749</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNqNkM1u1DAURi0EokPhFZB3rBL8FzveIKEptJWGIkERS8txbsBDEg920s7w9HWYMmu88ZXu9x1bByFMSUnzebstqZC6qJXQJSOUlUQwpsr9E7Q6LZ6iFcmrgkrGztCLlLaEEC4r8RydMcYrxnS9QukLuHAH8YBDh10Yk_NhTiOkhLvQ9-Hejz-wdfMEOB2G3RQGO3mHE_g_c4SE2xnwFLCDcYq2xyPEu9zP2TTBgP3YgZt8xuYRu5--byOML9GzzvYJXj3e5-jbxw-366ti8_nyev1-U7hKKFUIKoQEW2upLCe2I4LqWihCZKVB1NbVuraN1rRlTVu1XEtoFbG0aQVveWP5OXpz5O5i-D1Dmszgk4O-tyPkTxrNVM0FEzIn62PSxZBShM7soh9sPBhKzGLcbM0i1ixizWLc_DVu9rn6-vGRuRmgPRX_Kc6Bd8fAve_h8N9gc_FpfbOMGVAcAT473Z8ANv4yUnFVme83l-aWb9T66oKbr_wBBUyhSA</recordid><startdate>201204</startdate><enddate>201204</enddate><creator>KING, ELEANOR J</creator><creator>FERRIE, COLIN D</creator><creator>LIVINGSTON, JOHN H</creator><creator>TAYLOR, JOHN C</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201204</creationdate><title>Recovery of consciousness following acute symptomatic seizures due to central nervous system infections in children</title><author>KING, ELEANOR J ; FERRIE, COLIN D ; LIVINGSTON, JOHN H ; TAYLOR, JOHN C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5477-41446ea8967a30af041984700659e48ac898ab991d2bd5d396ed70a1bd43d3ba3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Acute Disease</topic><topic>Adolescent</topic><topic>Central Nervous System Infections - complications</topic><topic>Central Nervous System Infections - etiology</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Consciousness - physiology</topic><topic>Female</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>Meningitis, Aseptic - complications</topic><topic>Meningitis, Bacterial - complications</topic><topic>Postoperative Complications - physiopathology</topic><topic>Recovery of Function</topic><topic>Seizures - classification</topic><topic>Seizures - etiology</topic><topic>Seizures - parasitology</topic><topic>Seizures - virology</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KING, ELEANOR J</creatorcontrib><creatorcontrib>FERRIE, COLIN D</creatorcontrib><creatorcontrib>LIVINGSTON, JOHN H</creatorcontrib><creatorcontrib>TAYLOR, JOHN C</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Developmental medicine and child neurology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KING, ELEANOR J</au><au>FERRIE, COLIN D</au><au>LIVINGSTON, JOHN H</au><au>TAYLOR, JOHN C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Recovery of consciousness following acute symptomatic seizures due to central nervous system infections in children</atitle><jtitle>Developmental medicine and child neurology</jtitle><addtitle>Dev Med Child Neurol</addtitle><date>2012-04</date><risdate>2012</risdate><volume>54</volume><issue>4</issue><spage>324</spage><epage>327</epage><pages>324-327</pages><issn>0012-1622</issn><eissn>1469-8749</eissn><abstract>Aim The aim of this study was to assess whether acute symptomatic epileptic seizures associated with central nervous system infections (ASinf) have a different ictal and postictal course to seizures of other aetiologies.
Method A case note analysis of 81 children (47 males; 34 females; age range 1mo–15y 6mo; median age 12mo) with central nervous system infections was undertaken. Seizure type, duration, aetiology, and timing were recorded. Recovery time to full consciousness in those not intubated was determined. Intubation rates and recovery times were compared with those from previous studies.
Results Of the 81 children, 40 (49.4%) had one or more ASinf. The different aetiologies were bacterial meningitis, aseptic meningitis, abscess/empyema, encephalitis, and postoperative infection. Twenty‐two had status epilepticus. The intubation rate in children with ASinf was higher than that in children with seizures of other aetiologies (21/40 [52.5%] vs 4/124 [3.23%]; p < 0.0001). Median postictal recovery time was 4.33 hours (0–207h). Children with ASinf took 4.3 (p<0.01), 3.0 (p=0.004), and 8.8 (p<0.001) times longer to recover than children who had seizures from all causes, remote symptomatic seizures, and febrile seizures respectively.
Interpretation ASinf in children are often longer, more likely to be associated with status epilepticus, more likely to necessitate intubation, and take longer to recover from than seizures of other aetiologies. This may help in the early diagnosis of central nervous system infection in children presenting with seizures.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>22352298</pmid><doi>10.1111/j.1469-8749.2012.04227.x</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0012-1622 |
| ispartof | Developmental medicine and child neurology, 2012-04, Vol.54 (4), p.324-327 |
| issn | 0012-1622 1469-8749 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_927834246 |
| source | Wiley-Blackwell Read & Publish Collection |
| subjects | Acute Disease Adolescent Central Nervous System Infections - complications Central Nervous System Infections - etiology Child Child, Preschool Consciousness - physiology Female Humans Infant Infant, Newborn Male Meningitis, Aseptic - complications Meningitis, Bacterial - complications Postoperative Complications - physiopathology Recovery of Function Seizures - classification Seizures - etiology Seizures - parasitology Seizures - virology Time Factors |
| title | Recovery of consciousness following acute symptomatic seizures due to central nervous system infections in children |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T23%3A40%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Recovery%20of%20consciousness%20following%20acute%20symptomatic%20seizures%20due%20to%20central%20nervous%20system%20infections%20in%20children&rft.jtitle=Developmental%20medicine%20and%20child%20neurology&rft.au=KING,%20ELEANOR%20J&rft.date=2012-04&rft.volume=54&rft.issue=4&rft.spage=324&rft.epage=327&rft.pages=324-327&rft.issn=0012-1622&rft.eissn=1469-8749&rft_id=info:doi/10.1111/j.1469-8749.2012.04227.x&rft_dat=%3Cproquest_cross%3E927834246%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c5477-41446ea8967a30af041984700659e48ac898ab991d2bd5d396ed70a1bd43d3ba3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=927834246&rft_id=info:pmid/22352298&rfr_iscdi=true |