Prospective study of severity assessment and management of acute medical admissions with skin and soft tissue infection

Background Several severity scoring systems have been proposed for skin and soft tissue infections (SSTIs), but none has been tested prospectively. Methods We prospectively enrolled adult, acute medical admissions with SSTI between April 2009 and June 2010. Severity was assessed using two proposed S...

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Bibliographic Details
Published in:Journal of antimicrobial chemotherapy 2012-04, Vol.67 (4), p.1016-1019
Main Authors: Marwick, Charis, Rae, Nikolas, Irvine, Nicola, Davey, Peter
Format: Article
Language:English
Subjects:
Adult
Adults
Aged
Antibiotics
Antibiotics. Antiinfectious agents. Antiparasitic agents
Bacterial diseases
Bacterial sepsis
Biological and medical sciences
Female
Hospitalization - statistics & numerical data
Human bacterial diseases
Humans
Infections
Infectious diseases
Male
Medical sciences
Middle Aged
Patient admissions
Pharmacology. Drug treatments
Prospective Studies
Sepsis
Sepsis - diagnosis
Sepsis - pathology
Severity of Illness Index
Skin Diseases, Bacterial - complications
Skin Diseases, Bacterial - diagnosis
Skin Diseases, Bacterial - pathology
Soft Tissue Infections - complications
Soft Tissue Infections - diagnosis
Soft Tissue Infections - pathology
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Summary:Background Several severity scoring systems have been proposed for skin and soft tissue infections (SSTIs), but none has been tested prospectively. Methods We prospectively enrolled adult, acute medical admissions with SSTI between April 2009 and June 2010. Severity was assessed using two proposed SSTI scoring systems, one based on a generic sepsis definition. Antimicrobial prescribing was compared with guideline recommendations. Results We enrolled 79 patients. One of the scoring systems classified 47% into class I (no sepsis or comorbidity), 5% into class II (no sepsis, but comorbidity), 34% into class III [sepsis, but standardized early warning system (SEWS)
ISSN:0305-7453
1460-2091
DOI:10.1093/jac/dkr554