Porphyrin and phthalocyanine glycodendritic conjugates: synthesis, photophysical and photochemical properties

Synthesis of water soluble porphyrin and phthalocyanine derivatives with, respectively, eight and sixteen galactose units has been carried out. The combined preliminary photophysical and photochemical features of the new products suggest that they might be promising photodynamic therapeutic agents.

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2012-04, Vol.48 (30), p.3608-3610
Main Authors: Silva, Sandrina, Pereira, Patrícia M R, Silva, Patrícia, Paz, Filipe A Almeida, Faustino, Maria A F, Cavaleiro, José A S, Tomé, João P C
Format: Article
Language:English
Subjects:
Chemical compounds
Conjugates
Derivatives
Galactose
Galactose - chemistry
Galactose - radiation effects
Humans
Indoles - chemistry
Indoles - radiation effects
Pharmacology
Photochemical
Photochemical Processes
Photochemotherapy
Porphyrins
Porphyrins - chemistry
Porphyrins - radiation effects
Serum Albumin - chemistry
Singlet Oxygen - chemistry
Synthesis
Ultraviolet Rays
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Description
Summary:Synthesis of water soluble porphyrin and phthalocyanine derivatives with, respectively, eight and sixteen galactose units has been carried out. The combined preliminary photophysical and photochemical features of the new products suggest that they might be promising photodynamic therapeutic agents.
ISSN:1359-7345
1364-548X
DOI:10.1039/c2cc17561d