Caffeine modifies effects of X-ray action on mice after exposure to radiation and exhibits radioprotective properties

Caffeine stimulates the central nervous system and heart function, regulates blood pressure, improves efficiency and attention focusing, and reduces fatigue. The influence of caffeine on the modification of the radiation effect using different cultures of animal cells has been investigated. Asadulli...

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Bibliographic Details
Published in:Doklady. Biochemistry and biophysics 2012-02, Vol.442 (1), p.22-25
Main Authors: Asadullina, N. R., Gudkov, S. V., Bruskov, V. I.
Format: Article
Language:English
Subjects:
Animals
Biochemistry
Biological and Medical Physics
Biomedical and Life Sciences
Biophysics
Biophysics and Molecular Biology
Caffeine
Caffeine - administration & dosage
Caffeine - pharmacology
Dose-Response Relationship, Radiation
Granulocytes - cytology
Granulocytes - drug effects
Granulocytes - radiation effects
Injections
Leukocyte Count
Life Sciences
Male
Mice
Micronucleus Tests
Platelet Count
Radiation
Radiation-Protective Agents - administration & dosage
Radiation-Protective Agents - pharmacology
Rodents
Time Factors
X-Rays - adverse effects
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Summary:Caffeine stimulates the central nervous system and heart function, regulates blood pressure, improves efficiency and attention focusing, and reduces fatigue. The influence of caffeine on the modification of the radiation effect using different cultures of animal cells has been investigated. Asadullina et al studied the effect of the injection of caffeine to mice before and after irradiation. It was found that caffeine significantly modified the effect of radiation.
ISSN:1607-6729
1608-3091
DOI:10.1134/S1607672912010073