Cardiac biometry and function in euploid fetuses with intracardiac echogenic foci

ABSTRACT Objective To compare cardiac biometry and function between fetuses with and without intracardiac echogenic foci (ICEF). Methods One hundred and fifty‐two fetuses with ICEF were compared with 104 controls. Diastolic ventricular transverse diameters, systolic aortic and pulmonary diameters an...

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Published in:Prenatal diagnosis 2012-02, Vol.32 (2), p.113-116
Main Authors: Facio, María C., Hervías-Vivancos, Blas, Broullón, José Román, Avila, José, Fajardo-Expósito, María A., Bartha, José L.
Format: Article
Language:English
Subjects:
Adult
Biometry
Blood Flow Velocity - physiology
Body Mass Index
Echocardiography, Doppler - methods
Female
Fetal Diseases - diagnostic imaging
Fetal Diseases - physiopathology
Fetal Heart - diagnostic imaging
Fetal Heart - physiopathology
Gestational Age
Heart Atria - diagnostic imaging
Heart Atria - physiopathology
Heart Defects, Congenital - diagnostic imaging
Heart Defects, Congenital - physiopathology
Heart Ventricles - diagnostic imaging
Heart Ventricles - physiopathology
Hemodynamics
Humans
Maternal Age
Pregnancy
Ultrasonography, Prenatal
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Summary:ABSTRACT Objective To compare cardiac biometry and function between fetuses with and without intracardiac echogenic foci (ICEF). Methods One hundred and fifty‐two fetuses with ICEF were compared with 104 controls. Diastolic ventricular transverse diameters, systolic aortic and pulmonary diameters and interventricular septum were measured. Doppler measurements included pulmonary artery and aortic maximum systolic velocities, time to peak, velocity time integral and atrioventricular E/A ratios. Results Only A wave in the mitral valve was slightly but significantly higher in the ICEF group (0.45 ± 0.07 m/s vs 0.43 ± 0.08 m/s, p = 0.03), but mitral E/A ratio was similar in both groups (0.61 ± 0.06 vs 0.60 ± 0.07, p = 0.22). There were no statistically significant differences in the rest of the studied variables between the two groups. Conclusion Fetuses with ICEF do not have relevant abnormalities in either cardiac biometry or function. We suggest the presence of an isolated ICEF should not be an indication for fetal echocardiography as long as fetal morphology scan had been performed and revealed no other findings. © 2012 John Wiley & Sons, Ltd.
ISSN:0197-3851
1097-0223
DOI:10.1002/pd.2903