Peculiarities of bile formation in rats of different sex under estron influence

The influence of estron (8 microg/100g of animal's body weight) on the exocrine function of liver and the changes in bile acid composition of bile on different sex rats was studied. It was shown, that hormone at the applied dose, effected choleresis of female rats more effectively. Estron also...

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Bibliographic Details
Published in:Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) Ukraine : 1994), 2011, Vol.57 (6), p.52-57
Main Authors: Klymiuk, O V, Bondzyk, O V, Reshetnik, Ie M, Vesel's'kyĭ, S P, Makarchuk, M Iu
Format: Article
Language:Ukrainian
Subjects:
Animals
Bile - chemistry
Bile - secretion
Bile Acids and Salts - biosynthesis
Estrogens - pharmacology
Estrone - pharmacology
Female
Liver - drug effects
Liver - metabolism
Liver - secretion
Male
Rats
Sex Characteristics
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Summary:The influence of estron (8 microg/100g of animal's body weight) on the exocrine function of liver and the changes in bile acid composition of bile on different sex rats was studied. It was shown, that hormone at the applied dose, effected choleresis of female rats more effectively. Estron also caused different changes in bile composition. So, estron stimulated bile acid conjugation with taurine and glycin in female rat liver. Increasing of free and conjugated bile acid biosynthesis in male rats was observed.
ISSN:2522-9028