Parameters of Microcirculation in Paired Formations after Single Aspirin Administration: Laser Doppler Flowmetry Data

Laser Doppler flowmetry showed that aspirin can induce blood flow reduction and transitory manifold increase or decrease in vascular tone in rat skin and kidneys. The dynamics is more illustrative when parameters of individual animals are evaluated and depends on the areas of blood flow recording. D...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2011-05, Vol.151 (1), p.16-21
Main Authors: Mikhailichenko, L. A., Tikhomirova, I. A.
Format: Article
Language:English
Subjects:
Animals
Aspirin
Aspirin - administration & dosage
Aspirin - antagonists & inhibitors
Biomedical and Life Sciences
Biomedicine
Cardiac patients
Cell Biology
Internal Medicine
Kidney - blood supply
Kidney - drug effects
Laboratory Medicine
Laser-Doppler Flowmetry
Microcirculation - drug effects
Microvessels - drug effects
Pathology
Pentobarbital - administration & dosage
Pentobarbital - antagonists & inhibitors
Rats
Skin - blood supply
Skin - drug effects
Sleep - drug effects
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Description
Summary:Laser Doppler flowmetry showed that aspirin can induce blood flow reduction and transitory manifold increase or decrease in vascular tone in rat skin and kidneys. The dynamics is more illustrative when parameters of individual animals are evaluated and depends on the areas of blood flow recording. Deaths and reduction of narcotic sleep duration were noted in concomitant use of nembutal and aspirin.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-011-1249-4