Multiple myeloma presenting as solitary mass in the posterior fossa

Abstract Intracranial plasma cell tumors are extremely rare and can either be solitary lesions or part of systemic multiple myeloma. We report a 42-year-old woman who presented with a posterior fossa mass and successfully underwent surgical resection, leading to the diagnosis of multiple myeloma. To...

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Bibliographic Details
Published in:Journal of clinical neuroscience 2010-11, Vol.17 (11), p.1457-1459
Main Authors: Patel, A.J, Adams, G.J, Humphries, W.E, Rao, V.Y, Fox, B.D, Fridley, J, Gopinath, S.P
Format: Article
Language:English
Subjects:
Adult
Brain tumor
Cranial Fossa, Posterior - diagnostic imaging
Cranial Fossa, Posterior - pathology
Cranial Fossa, Posterior - surgery
Craniotomy
Diagnosis, Differential
Female
Humans
Infratentorial Neoplasms - diagnosis
Infratentorial Neoplasms - diagnostic imaging
Infratentorial Neoplasms - surgery
Meningioma
Multiple myeloma
Multiple Myeloma - diagnosis
Multiple Myeloma - diagnostic imaging
Multiple Myeloma - surgery
Neurology
Occipital Bone - diagnostic imaging
Occipital Bone - pathology
Occipital Bone - surgery
Plasma cell tumor
Plasmacytoma
Posterior fossa
Radiography
Skull Base Neoplasms - diagnosis
Skull Base Neoplasms - diagnostic imaging
Skull Base Neoplasms - surgery
Treatment Outcome
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Summary:Abstract Intracranial plasma cell tumors are extremely rare and can either be solitary lesions or part of systemic multiple myeloma. We report a 42-year-old woman who presented with a posterior fossa mass and successfully underwent surgical resection, leading to the diagnosis of multiple myeloma. To our knowledge, this is the first reported case of multiple myeloma presenting as a posterior fossa mass lesion. This report highlights the importance of maintaining plasma cell tumor in the differential of intracranial mass with bony involvement. Furthermore, once the diagnosis is established, further work up is critical to evaluate for systemic disease.
ISSN:0967-5868
1532-2653
DOI:10.1016/j.jocn.2010.03.033