Synthesis, antimicrobial and antioxidant evaluation of quinolines and bis(indolyl)methanes

An improved and practical synthesis of substituted quinolines and bis(indolyl)methanes was achieved under microwave condition using Zn(OTf) 2 as catalyst. The synthesized compounds have been screened for antimicrobial and antioxidant activities.

Saved in:
Bibliographic Details
Published in:Bioorganic & medicinal chemistry letters 2010-12, Vol.20 (24), p.7292-7296
Main Authors: Praveen, C., DheenKumar, P., Muralidharan, D., Perumal, P.T.
Format: Article
Language:English
Subjects:
Anti-Infective Agents - chemical synthesis
Anti-Infective Agents - chemistry
Anti-Infective Agents - pharmacology
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antimicrobial and antioxidant properties
Biological and medical sciences
Bis(indolyl)methanes
Catalysis
Free Radical Scavengers - chemical synthesis
Free Radical Scavengers - chemistry
Free Radical Scavengers - pharmacology
General aspects
Hydrogen Peroxide - chemistry
Indoles
Medical sciences
Methane - chemical synthesis
Methane - chemistry
Methane - pharmacology
Microbial Sensitivity Tests
Microwave condition
Microwaves
Pharmacology. Drug treatments
Quinolines
Quinolines - chemical synthesis
Quinolines - chemistry
Quinolines - pharmacology
Zn(OTf) 2
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:An improved and practical synthesis of substituted quinolines and bis(indolyl)methanes was achieved under microwave condition using Zn(OTf) 2 as catalyst. The synthesized compounds have been screened for antimicrobial and antioxidant activities.
ISSN:0960-894X
1464-3405
DOI:10.1016/j.bmcl.2010.10.075