Precision of the gallbladder ejection fraction obtained with Tc-99m-pyridoxyl-5-methyl-tryptophan ( super(99m)Tc-PMT) hepatobiliary scintigraphy as compared with the contraction ratio in three-dimensional computed tomography

• Published in: Annals of nuclear medicine 1997-06, Vol.11 (2), p.123-128
• Main Authors: Uchiyama, Katsuhiro, Kuniyasu, Yoshio, Higashi, Suminori T, Shen, Yun, Niio, Yasuo, Hasebe, Shin, Matsuoka, Shin, Shima, Hideki, Shinohara, Hiroyuki, Takizawa, Kenji, Obuchi, Masao, Honda, Minoru, Hirata, Nobuto
• Format: Article
• Language: English
• ISSN: 0914-7187; 1864-6433
• DOI: 10.1007/BF03164820

The gallbladder ejection fraction (GBEF) obtained with Tc-99m-pyridoxyl-5-methyl-tryptophan ( super(99m)Tc-PMT) hepatobiliary scintigraphy has been used as a parameter of gallbladder function. To determine the accuracy of GBEF, the relationship with the contraction ratio of the gallbladder (GBCR) obtained with three-dimensional helical computed tomography (3D-CT) was studied.Patients and methods: A normal volunteer, 8 patients suffering from cholecystolithiasis and a patient with gallbladder dyskinesia were examined. The percent initial dose (%ID) for the gallbladder and GBEF with hepatobiliary scintigraphy were used to compare the volume of the gallbladder and GBCR which was measured by 3D-CT.Results: The %ID of the gallbladder was correlated with the volume of the gallbladder by 3D-CT (Y=1.000X- 1.818, r= 0.928). GBEF was correlated well with GBCR by 3D-CT (Y= 0.916X + 6.296, r = 0.975).Conclusions: The %ID of the gallbladder obtained with hepatobiliary scintigraphy may be a good indicator of the volume of the gallbladder. The accuracy of GBEF was confirmed by comparison with 3D-CT examination. GBEF is considered a useful parameter of pathophysiological gallbladder function.