Total Raltegravir Concentrations in Cerebrospinal Fluid Exceed the 50-Percent Inhibitory Concentration for Wild-Type HIV-1

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Published in:Antimicrobial Agents and Chemotherapy 2010-12, Vol.54 (12), p.5156-5160
Main Authors: CROTEAU, David, LETENDRE, Scott, MCCUTCHAN, Allen, MORGELLO, Susan, SIMPSON, David, WAY, Lauren, VAIDA, Florin, UELAND, Susan, CAPPARELLI, Edmund, GRANT, Igor, BEST, Brookie M, ELLIS, Ronald J, BREIDINGER, Sheila, CLIFFORD, David, COLLIER, Ann, GELMAN, Benjamin, MARRA, Christina, MBEO, Gilbert
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
Adult
Aged
Anti-HIV Agents
Anti-HIV Agents - blood
Anti-HIV Agents - cerebrospinal fluid
Anti-HIV Agents - therapeutic use
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antiviral agents
Biological and medical sciences
CD4 antigen
Cerebrospinal fluid
Chromatography, Liquid
Cognition
Female
Hepatitis C virus
HIV Infections
HIV Infections - drug therapy
HIV Infections - virology
Human immunodeficiency virus 1
Human viral diseases
Humans
Immunodeficiencies
Immunodeficiencies. Immunoglobulinopathies
Immunopathology
Infection
Infectious diseases
Inhibitory Concentration 50
Male
Mass spectroscopy
Medical sciences
Middle Aged
Nervous system
Pharmacology
Pharmacology. Drug treatments
Polymerase chain reaction
Replication
Reverse Transcriptase Polymerase Chain Reaction
Ritonavir
Ritonavir - blood
Ritonavir - cerebrospinal fluid
Ritonavir - therapeutic use
RNA
Sampling
Tandem Mass Spectrometry
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
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Summary:Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.00507-10