B-vitamin intake in human pregnancy and imprinted gene methylation in the offspring

The ultimate methyl donor for methylation reactions is the folate-methylation cycle and feeding pregnant dams diets deficient in methyl donors results in altered regulation of specific genes in the offspring which are under imprinting control(2).

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Bibliographic Details
Published in:Proceedings of the Nutrition Society 2010, Vol.69 (OCE6), p.E489-E489, Article E489
Main Authors: Haggarty, P., Campbell, D. M., Andrews, K., Hoad, G., McNeill, G.
Format: Article
Language:English
Subjects:
Diet
Methylation
Nutrition
Offspring
Pregnancy
Vitamin B
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Description
Summary:The ultimate methyl donor for methylation reactions is the folate-methylation cycle and feeding pregnant dams diets deficient in methyl donors results in altered regulation of specific genes in the offspring which are under imprinting control(2).
ISSN:0029-6651
1475-2719
DOI:10.1017/S0029665110003526