Non-secretory solitary plasmacytoma of the spleen

A case of primary nonsecretory plasmacytoma of the spleen is reported. On laparotomy and splenectomy a 920 g spleen was removed, measuring 16 x 14 x 6 cm. The cut surface of the entire spleen showed that the tumour occupied most of the splenic tissue. A bone marrow aspirate and trephine, skeletal su...

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Bibliographic Details
Published in:Cancer Immunology, Immunotherapy Immunotherapy, 1998-12, Vol.15 (4), p.286-288
Main Authors: COLOVIC, M. D, JANKOVIC, G. M, COLOVIC, R. B, MARTINOVIC-CEMERIKIC, V. M
Format: Article
Language:English
Subjects:
Antineoplastic agents
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Biological and medical sciences
Biopsy
Bone marrow
Cancer
Carmustine - therapeutic use
Chemotherapy
Cyclophosphamide - therapeutic use
Humans
Immunocytochemistry
Immunotherapy
Liver
Lymph nodes
Male
Medical sciences
Melphalan - therapeutic use
Middle Aged
Myeloma
Oncology
Pharmacology. Drug treatments
Plasma cells
Plasmacytoma
Plasmacytoma - drug therapy
Plasmacytoma - pathology
Plasmacytoma - surgery
Prednisone - therapeutic use
Spleen
Splenectomy
Splenic Neoplasms - drug therapy
Splenic Neoplasms - pathology
Splenic Neoplasms - surgery
Vincristine - therapeutic use
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Summary:A case of primary nonsecretory plasmacytoma of the spleen is reported. On laparotomy and splenectomy a 920 g spleen was removed, measuring 16 x 14 x 6 cm. The cut surface of the entire spleen showed that the tumour occupied most of the splenic tissue. A bone marrow aspirate and trephine, skeletal survey showed no signs of myeloma. Biopsy of the liver and regional lymph nodes was normal. Immunocytochemistry of the splenic tumour showed positivity for pan-B and plasma cell markers. After splenectomy the patient was treated with chemotherapy according to protocol VBCMP (M2).
ISSN:1357-0560
1559-131X
1432-0851
DOI:10.1007/bf02787215