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Vitamin D status in relation to postural stability in the elderly

Objectives Postural instability (PI) is an important risk factor for falls, especially in the frail older population. In this study, we investigated the impact of vitamin D deficiency on PI in a sample of community dwelling older subjects. Our objective was to determine the potential association bet...

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Published in:The Journal of nutrition, health & aging health & aging, 2012-03, Vol.16 (3), p.270-275
Main Authors: Boersma, D., Demontiero, O., Amiri, Z. Mohtasham, Hassan, S., Suarez, H., Geisinger, D., Suriyaarachchi, P., Sharma, A., Duque, Gustavo
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cited_by cdi_FETCH-LOGICAL-c510t-f54757cdca0cf94964177ebfa163e57e59ed98af4a86ba6901f63bcea9814a9b3
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container_title The Journal of nutrition, health & aging
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creator Boersma, D.
Demontiero, O.
Amiri, Z. Mohtasham
Hassan, S.
Suarez, H.
Geisinger, D.
Suriyaarachchi, P.
Sharma, A.
Duque, Gustavo
description Objectives Postural instability (PI) is an important risk factor for falls, especially in the frail older population. In this study, we investigated the impact of vitamin D deficiency on PI in a sample of community dwelling older subjects. Our objective was to determine the potential association between vitamin D deficiency and PI in older fallers. Design Cross-sectional study. Setting Falls and Fractures Clinic, Department of Geriatric Medicine, Nepean Hospital, Penrith, Australia. Participants One hundred and forty-five adults aged 65 years and older who have had at least one episode of a fall within the six months prior to assessment at the Falls and Fractures Clinic. Measurements Serum 25(OH) vitamin D3 [25(OH)D3] and parathyroid hormone concentrations were determined at baseline. Subjects were separated into 3 groups based on serum 25(OH)D3 levels with the following cut-off values: < 30 nmol/L (deficient), 30–50 nmol/L (insufficient) and > 50 nmol/L (normal). Other baseline measurements included body mass index, mini-nutritional assessment, grip strength, serum calcium concentration and creatinine clearance, which were used as covariables. PI was assessed using a computerized virtual reality system (Medicaa, Uruguay). Measured parameters included limits of stability (LOS) and centre of pressure (COP) under eyes closed on foam (ECF) and visio-vestibular stimulation. The estimated swaying area, computed from the ellipse of confidence under eyes closed standing on foam (ECF), was also used as a PI parameter. Gait velocity (GV) was measured using a GaitRITE walkway system. Results Posture was impaired in vitamin D deficiency (
doi_str_mv 10.1007/s12603-011-0345-5
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Mohtasham ; Hassan, S. ; Suarez, H. ; Geisinger, D. ; Suriyaarachchi, P. ; Sharma, A. ; Duque, Gustavo</creator><creatorcontrib>Boersma, D. ; Demontiero, O. ; Amiri, Z. Mohtasham ; Hassan, S. ; Suarez, H. ; Geisinger, D. ; Suriyaarachchi, P. ; Sharma, A. ; Duque, Gustavo</creatorcontrib><description>Objectives Postural instability (PI) is an important risk factor for falls, especially in the frail older population. In this study, we investigated the impact of vitamin D deficiency on PI in a sample of community dwelling older subjects. Our objective was to determine the potential association between vitamin D deficiency and PI in older fallers. Design Cross-sectional study. Setting Falls and Fractures Clinic, Department of Geriatric Medicine, Nepean Hospital, Penrith, Australia. Participants One hundred and forty-five adults aged 65 years and older who have had at least one episode of a fall within the six months prior to assessment at the Falls and Fractures Clinic. Measurements Serum 25(OH) vitamin D3 [25(OH)D3] and parathyroid hormone concentrations were determined at baseline. Subjects were separated into 3 groups based on serum 25(OH)D3 levels with the following cut-off values: &lt; 30 nmol/L (deficient), 30–50 nmol/L (insufficient) and &gt; 50 nmol/L (normal). Other baseline measurements included body mass index, mini-nutritional assessment, grip strength, serum calcium concentration and creatinine clearance, which were used as covariables. PI was assessed using a computerized virtual reality system (Medicaa, Uruguay). Measured parameters included limits of stability (LOS) and centre of pressure (COP) under eyes closed on foam (ECF) and visio-vestibular stimulation. The estimated swaying area, computed from the ellipse of confidence under eyes closed standing on foam (ECF), was also used as a PI parameter. Gait velocity (GV) was measured using a GaitRITE walkway system. Results Posture was impaired in vitamin D deficiency (&lt;30 nmol/L) as indicated by lower LOS (90 +/− 18), higher ECF (25 +/− 10) and slower GV (55 +/− 7) as compared with the insufficient and normal groups. After adjustment for demographic, biochemical and anthropometric variables, vitamin D deficiency significantly correlated with low LOS and high COP under ECF. Conclusion Low levels of vitamin D were associated with PI. This association could also have an effect on slow GV and increased risk of falls. In conclusion, using an objective method to measure balance in older fallers we have identified a novel role of vitamin D in balance control. Prospective studies are required to confirm the effect of vitamin D on PI and elucidate the mechanisms of this association.</description><identifier>ISSN: 1279-7707</identifier><identifier>EISSN: 1760-4788</identifier><identifier>DOI: 10.1007/s12603-011-0345-5</identifier><identifier>PMID: 22456785</identifier><language>eng</language><publisher>Paris: Springer-Verlag</publisher><subject>Accidental Falls - prevention &amp; control ; Accidental Falls - statistics &amp; numerical data ; Aged ; Aging ; Australia ; Balance ; Biological and medical sciences ; Bones ; Cross-Sectional Studies ; Disease ; Falls ; Feeding. Feeding behavior ; Female ; Fractures ; Fundamental and applied biological sciences. Psychology ; Gait ; Gait - physiology ; Geriatric Assessment ; Geriatrics ; Geriatrics/Gerontology ; Hospitals ; Humans ; Male ; Medicine ; Medicine &amp; Public Health ; Motor Activity - physiology ; Muscle Strength - physiology ; Neurosciences ; Nutrition ; Nutrition Assessment ; Nutritional Status ; Older people ; Parathyroid Hormone - blood ; Parkinson's disease ; Population ; Posture ; Posture - physiology ; Primary Care Medicine ; Quality of Life Research ; Risk Factors ; Vertebrates: anatomy and physiology, studies on body, several organs or systems ; Vitamin D ; Vitamin D - analogs &amp; derivatives ; Vitamin D - blood ; Vitamin D Deficiency - blood ; Vitamin D Deficiency - complications ; Vitamin D Status in Relation to Postural Stability in the Elderly ; Vitamin deficiency</subject><ispartof>The Journal of nutrition, health &amp; aging, 2012-03, Vol.16 (3), p.270-275</ispartof><rights>Serdi and Springer Verlag France 2012</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c510t-f54757cdca0cf94964177ebfa163e57e59ed98af4a86ba6901f63bcea9814a9b3</citedby><cites>FETCH-LOGICAL-c510t-f54757cdca0cf94964177ebfa163e57e59ed98af4a86ba6901f63bcea9814a9b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=25665799$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22456785$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Boersma, D.</creatorcontrib><creatorcontrib>Demontiero, O.</creatorcontrib><creatorcontrib>Amiri, Z. Mohtasham</creatorcontrib><creatorcontrib>Hassan, S.</creatorcontrib><creatorcontrib>Suarez, H.</creatorcontrib><creatorcontrib>Geisinger, D.</creatorcontrib><creatorcontrib>Suriyaarachchi, P.</creatorcontrib><creatorcontrib>Sharma, A.</creatorcontrib><creatorcontrib>Duque, Gustavo</creatorcontrib><title>Vitamin D status in relation to postural stability in the elderly</title><title>The Journal of nutrition, health &amp; aging</title><addtitle>J Nutr Health Aging</addtitle><addtitle>J Nutr Health Aging</addtitle><description>Objectives Postural instability (PI) is an important risk factor for falls, especially in the frail older population. In this study, we investigated the impact of vitamin D deficiency on PI in a sample of community dwelling older subjects. Our objective was to determine the potential association between vitamin D deficiency and PI in older fallers. Design Cross-sectional study. Setting Falls and Fractures Clinic, Department of Geriatric Medicine, Nepean Hospital, Penrith, Australia. Participants One hundred and forty-five adults aged 65 years and older who have had at least one episode of a fall within the six months prior to assessment at the Falls and Fractures Clinic. Measurements Serum 25(OH) vitamin D3 [25(OH)D3] and parathyroid hormone concentrations were determined at baseline. Subjects were separated into 3 groups based on serum 25(OH)D3 levels with the following cut-off values: &lt; 30 nmol/L (deficient), 30–50 nmol/L (insufficient) and &gt; 50 nmol/L (normal). Other baseline measurements included body mass index, mini-nutritional assessment, grip strength, serum calcium concentration and creatinine clearance, which were used as covariables. PI was assessed using a computerized virtual reality system (Medicaa, Uruguay). Measured parameters included limits of stability (LOS) and centre of pressure (COP) under eyes closed on foam (ECF) and visio-vestibular stimulation. The estimated swaying area, computed from the ellipse of confidence under eyes closed standing on foam (ECF), was also used as a PI parameter. Gait velocity (GV) was measured using a GaitRITE walkway system. Results Posture was impaired in vitamin D deficiency (&lt;30 nmol/L) as indicated by lower LOS (90 +/− 18), higher ECF (25 +/− 10) and slower GV (55 +/− 7) as compared with the insufficient and normal groups. After adjustment for demographic, biochemical and anthropometric variables, vitamin D deficiency significantly correlated with low LOS and high COP under ECF. Conclusion Low levels of vitamin D were associated with PI. This association could also have an effect on slow GV and increased risk of falls. 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Mohtasham</au><au>Hassan, S.</au><au>Suarez, H.</au><au>Geisinger, D.</au><au>Suriyaarachchi, P.</au><au>Sharma, A.</au><au>Duque, Gustavo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vitamin D status in relation to postural stability in the elderly</atitle><jtitle>The Journal of nutrition, health &amp; aging</jtitle><stitle>J Nutr Health Aging</stitle><addtitle>J Nutr Health Aging</addtitle><date>2012-03-01</date><risdate>2012</risdate><volume>16</volume><issue>3</issue><spage>270</spage><epage>275</epage><pages>270-275</pages><issn>1279-7707</issn><eissn>1760-4788</eissn><abstract>Objectives Postural instability (PI) is an important risk factor for falls, especially in the frail older population. In this study, we investigated the impact of vitamin D deficiency on PI in a sample of community dwelling older subjects. Our objective was to determine the potential association between vitamin D deficiency and PI in older fallers. Design Cross-sectional study. Setting Falls and Fractures Clinic, Department of Geriatric Medicine, Nepean Hospital, Penrith, Australia. Participants One hundred and forty-five adults aged 65 years and older who have had at least one episode of a fall within the six months prior to assessment at the Falls and Fractures Clinic. Measurements Serum 25(OH) vitamin D3 [25(OH)D3] and parathyroid hormone concentrations were determined at baseline. Subjects were separated into 3 groups based on serum 25(OH)D3 levels with the following cut-off values: &lt; 30 nmol/L (deficient), 30–50 nmol/L (insufficient) and &gt; 50 nmol/L (normal). Other baseline measurements included body mass index, mini-nutritional assessment, grip strength, serum calcium concentration and creatinine clearance, which were used as covariables. PI was assessed using a computerized virtual reality system (Medicaa, Uruguay). Measured parameters included limits of stability (LOS) and centre of pressure (COP) under eyes closed on foam (ECF) and visio-vestibular stimulation. The estimated swaying area, computed from the ellipse of confidence under eyes closed standing on foam (ECF), was also used as a PI parameter. Gait velocity (GV) was measured using a GaitRITE walkway system. Results Posture was impaired in vitamin D deficiency (&lt;30 nmol/L) as indicated by lower LOS (90 +/− 18), higher ECF (25 +/− 10) and slower GV (55 +/− 7) as compared with the insufficient and normal groups. After adjustment for demographic, biochemical and anthropometric variables, vitamin D deficiency significantly correlated with low LOS and high COP under ECF. Conclusion Low levels of vitamin D were associated with PI. This association could also have an effect on slow GV and increased risk of falls. In conclusion, using an objective method to measure balance in older fallers we have identified a novel role of vitamin D in balance control. Prospective studies are required to confirm the effect of vitamin D on PI and elucidate the mechanisms of this association.</abstract><cop>Paris</cop><pub>Springer-Verlag</pub><pmid>22456785</pmid><doi>10.1007/s12603-011-0345-5</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record>
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subjects Accidental Falls - prevention & control
Accidental Falls - statistics & numerical data
Aged
Aging
Australia
Balance
Biological and medical sciences
Bones
Cross-Sectional Studies
Disease
Falls
Feeding. Feeding behavior
Female
Fractures
Fundamental and applied biological sciences. Psychology
Gait
Gait - physiology
Geriatric Assessment
Geriatrics
Geriatrics/Gerontology
Hospitals
Humans
Male
Medicine
Medicine & Public Health
Motor Activity - physiology
Muscle Strength - physiology
Neurosciences
Nutrition
Nutrition Assessment
Nutritional Status
Older people
Parathyroid Hormone - blood
Parkinson's disease
Population
Posture
Posture - physiology
Primary Care Medicine
Quality of Life Research
Risk Factors
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Vitamin D
Vitamin D - analogs & derivatives
Vitamin D - blood
Vitamin D Deficiency - blood
Vitamin D Deficiency - complications
Vitamin D Status in Relation to Postural Stability in the Elderly
Vitamin deficiency
title Vitamin D status in relation to postural stability in the elderly
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