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Vitamin D status in relation to postural stability in the elderly
Objectives Postural instability (PI) is an important risk factor for falls, especially in the frail older population. In this study, we investigated the impact of vitamin D deficiency on PI in a sample of community dwelling older subjects. Our objective was to determine the potential association bet...
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Published in: | The Journal of nutrition, health & aging health & aging, 2012-03, Vol.16 (3), p.270-275 |
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creator | Boersma, D. Demontiero, O. Amiri, Z. Mohtasham Hassan, S. Suarez, H. Geisinger, D. Suriyaarachchi, P. Sharma, A. Duque, Gustavo |
description | Objectives
Postural instability (PI) is an important risk factor for falls, especially in the frail older population. In this study, we investigated the impact of vitamin D deficiency on PI in a sample of community dwelling older subjects. Our objective was to determine the potential association between vitamin D deficiency and PI in older fallers.
Design
Cross-sectional study.
Setting
Falls and Fractures Clinic, Department of Geriatric Medicine, Nepean Hospital, Penrith, Australia.
Participants
One hundred and forty-five adults aged 65 years and older who have had at least one episode of a fall within the six months prior to assessment at the Falls and Fractures Clinic.
Measurements
Serum 25(OH) vitamin D3 [25(OH)D3] and parathyroid hormone concentrations were determined at baseline. Subjects were separated into 3 groups based on serum 25(OH)D3 levels with the following cut-off values: < 30 nmol/L (deficient), 30–50 nmol/L (insufficient) and > 50 nmol/L (normal). Other baseline measurements included body mass index, mini-nutritional assessment, grip strength, serum calcium concentration and creatinine clearance, which were used as covariables. PI was assessed using a computerized virtual reality system (Medicaa, Uruguay). Measured parameters included limits of stability (LOS) and centre of pressure (COP) under eyes closed on foam (ECF) and visio-vestibular stimulation. The estimated swaying area, computed from the ellipse of confidence under eyes closed standing on foam (ECF), was also used as a PI parameter. Gait velocity (GV) was measured using a GaitRITE walkway system.
Results
Posture was impaired in vitamin D deficiency ( |
doi_str_mv | 10.1007/s12603-011-0345-5 |
format | article |
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Postural instability (PI) is an important risk factor for falls, especially in the frail older population. In this study, we investigated the impact of vitamin D deficiency on PI in a sample of community dwelling older subjects. Our objective was to determine the potential association between vitamin D deficiency and PI in older fallers.
Design
Cross-sectional study.
Setting
Falls and Fractures Clinic, Department of Geriatric Medicine, Nepean Hospital, Penrith, Australia.
Participants
One hundred and forty-five adults aged 65 years and older who have had at least one episode of a fall within the six months prior to assessment at the Falls and Fractures Clinic.
Measurements
Serum 25(OH) vitamin D3 [25(OH)D3] and parathyroid hormone concentrations were determined at baseline. Subjects were separated into 3 groups based on serum 25(OH)D3 levels with the following cut-off values: < 30 nmol/L (deficient), 30–50 nmol/L (insufficient) and > 50 nmol/L (normal). Other baseline measurements included body mass index, mini-nutritional assessment, grip strength, serum calcium concentration and creatinine clearance, which were used as covariables. PI was assessed using a computerized virtual reality system (Medicaa, Uruguay). Measured parameters included limits of stability (LOS) and centre of pressure (COP) under eyes closed on foam (ECF) and visio-vestibular stimulation. The estimated swaying area, computed from the ellipse of confidence under eyes closed standing on foam (ECF), was also used as a PI parameter. Gait velocity (GV) was measured using a GaitRITE walkway system.
Results
Posture was impaired in vitamin D deficiency (<30 nmol/L) as indicated by lower LOS (90 +/− 18), higher ECF (25 +/− 10) and slower GV (55 +/− 7) as compared with the insufficient and normal groups. After adjustment for demographic, biochemical and anthropometric variables, vitamin D deficiency significantly correlated with low LOS and high COP under ECF.
Conclusion
Low levels of vitamin D were associated with PI. This association could also have an effect on slow GV and increased risk of falls. In conclusion, using an objective method to measure balance in older fallers we have identified a novel role of vitamin D in balance control. Prospective studies are required to confirm the effect of vitamin D on PI and elucidate the mechanisms of this association.</description><identifier>ISSN: 1279-7707</identifier><identifier>EISSN: 1760-4788</identifier><identifier>DOI: 10.1007/s12603-011-0345-5</identifier><identifier>PMID: 22456785</identifier><language>eng</language><publisher>Paris: Springer-Verlag</publisher><subject>Accidental Falls - prevention & control ; Accidental Falls - statistics & numerical data ; Aged ; Aging ; Australia ; Balance ; Biological and medical sciences ; Bones ; Cross-Sectional Studies ; Disease ; Falls ; Feeding. Feeding behavior ; Female ; Fractures ; Fundamental and applied biological sciences. Psychology ; Gait ; Gait - physiology ; Geriatric Assessment ; Geriatrics ; Geriatrics/Gerontology ; Hospitals ; Humans ; Male ; Medicine ; Medicine & Public Health ; Motor Activity - physiology ; Muscle Strength - physiology ; Neurosciences ; Nutrition ; Nutrition Assessment ; Nutritional Status ; Older people ; Parathyroid Hormone - blood ; Parkinson's disease ; Population ; Posture ; Posture - physiology ; Primary Care Medicine ; Quality of Life Research ; Risk Factors ; Vertebrates: anatomy and physiology, studies on body, several organs or systems ; Vitamin D ; Vitamin D - analogs & derivatives ; Vitamin D - blood ; Vitamin D Deficiency - blood ; Vitamin D Deficiency - complications ; Vitamin D Status in Relation to Postural Stability in the Elderly ; Vitamin deficiency</subject><ispartof>The Journal of nutrition, health & aging, 2012-03, Vol.16 (3), p.270-275</ispartof><rights>Serdi and Springer Verlag France 2012</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c510t-f54757cdca0cf94964177ebfa163e57e59ed98af4a86ba6901f63bcea9814a9b3</citedby><cites>FETCH-LOGICAL-c510t-f54757cdca0cf94964177ebfa163e57e59ed98af4a86ba6901f63bcea9814a9b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=25665799$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22456785$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Boersma, D.</creatorcontrib><creatorcontrib>Demontiero, O.</creatorcontrib><creatorcontrib>Amiri, Z. Mohtasham</creatorcontrib><creatorcontrib>Hassan, S.</creatorcontrib><creatorcontrib>Suarez, H.</creatorcontrib><creatorcontrib>Geisinger, D.</creatorcontrib><creatorcontrib>Suriyaarachchi, P.</creatorcontrib><creatorcontrib>Sharma, A.</creatorcontrib><creatorcontrib>Duque, Gustavo</creatorcontrib><title>Vitamin D status in relation to postural stability in the elderly</title><title>The Journal of nutrition, health & aging</title><addtitle>J Nutr Health Aging</addtitle><addtitle>J Nutr Health Aging</addtitle><description>Objectives
Postural instability (PI) is an important risk factor for falls, especially in the frail older population. In this study, we investigated the impact of vitamin D deficiency on PI in a sample of community dwelling older subjects. Our objective was to determine the potential association between vitamin D deficiency and PI in older fallers.
Design
Cross-sectional study.
Setting
Falls and Fractures Clinic, Department of Geriatric Medicine, Nepean Hospital, Penrith, Australia.
Participants
One hundred and forty-five adults aged 65 years and older who have had at least one episode of a fall within the six months prior to assessment at the Falls and Fractures Clinic.
Measurements
Serum 25(OH) vitamin D3 [25(OH)D3] and parathyroid hormone concentrations were determined at baseline. Subjects were separated into 3 groups based on serum 25(OH)D3 levels with the following cut-off values: < 30 nmol/L (deficient), 30–50 nmol/L (insufficient) and > 50 nmol/L (normal). Other baseline measurements included body mass index, mini-nutritional assessment, grip strength, serum calcium concentration and creatinine clearance, which were used as covariables. PI was assessed using a computerized virtual reality system (Medicaa, Uruguay). Measured parameters included limits of stability (LOS) and centre of pressure (COP) under eyes closed on foam (ECF) and visio-vestibular stimulation. The estimated swaying area, computed from the ellipse of confidence under eyes closed standing on foam (ECF), was also used as a PI parameter. Gait velocity (GV) was measured using a GaitRITE walkway system.
Results
Posture was impaired in vitamin D deficiency (<30 nmol/L) as indicated by lower LOS (90 +/− 18), higher ECF (25 +/− 10) and slower GV (55 +/− 7) as compared with the insufficient and normal groups. After adjustment for demographic, biochemical and anthropometric variables, vitamin D deficiency significantly correlated with low LOS and high COP under ECF.
Conclusion
Low levels of vitamin D were associated with PI. This association could also have an effect on slow GV and increased risk of falls. In conclusion, using an objective method to measure balance in older fallers we have identified a novel role of vitamin D in balance control. Prospective studies are required to confirm the effect of vitamin D on PI and elucidate the mechanisms of this association.</description><subject>Accidental Falls - prevention & control</subject><subject>Accidental Falls - statistics & numerical data</subject><subject>Aged</subject><subject>Aging</subject><subject>Australia</subject><subject>Balance</subject><subject>Biological and medical sciences</subject><subject>Bones</subject><subject>Cross-Sectional Studies</subject><subject>Disease</subject><subject>Falls</subject><subject>Feeding. Feeding behavior</subject><subject>Female</subject><subject>Fractures</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Gait</subject><subject>Gait - physiology</subject><subject>Geriatric Assessment</subject><subject>Geriatrics</subject><subject>Geriatrics/Gerontology</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Motor Activity - physiology</subject><subject>Muscle Strength - physiology</subject><subject>Neurosciences</subject><subject>Nutrition</subject><subject>Nutrition Assessment</subject><subject>Nutritional Status</subject><subject>Older people</subject><subject>Parathyroid Hormone - blood</subject><subject>Parkinson's disease</subject><subject>Population</subject><subject>Posture</subject><subject>Posture - physiology</subject><subject>Primary Care Medicine</subject><subject>Quality of Life Research</subject><subject>Risk Factors</subject><subject>Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><subject>Vitamin D</subject><subject>Vitamin D - analogs & derivatives</subject><subject>Vitamin D - blood</subject><subject>Vitamin D Deficiency - blood</subject><subject>Vitamin D Deficiency - complications</subject><subject>Vitamin D Status in Relation to Postural Stability in the Elderly</subject><subject>Vitamin deficiency</subject><issn>1279-7707</issn><issn>1760-4788</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNp10EtLAzEQB_Agiq3VD-BFFkQ8rSa7eR5LfULBi3oNs2lWt6S7Ncke-u1N2fpA8JSB-c1k-CN0SvAVwVhcB1JwXOaYkByXlOVsD42J4DinQsr9VBdC5UJgMUJHISwxpkxJfohGRUEZF5KN0fS1ibBq2uwmCxFiH7JUe-sgNl2bxS5bdyH2Hty2XTWuiZutiO82s25hvdsco4MaXLAnu3eCXu5un2cP-fzp_nE2neeGERzzmlHBhFkYwKZWVHFKhLBVDYSXlgnLlF0oCTUFySvgCpOal5WxoCShoKpygi6HvWvfffQ2RL1qgrHOQWu7PmjFSyqVFCTJ8z9y2fW-TcdpgkkKiigmkyKDMr4Lwdtar32zAr9JSG_j1UO8OsWrt_FqlmbOdpv7amUX3xNfeSZwsQMQDLjaQ2ua8OMY50wolVwxuJBa7Zv1v0_87_dPVdyRQw</recordid><startdate>20120301</startdate><enddate>20120301</enddate><creator>Boersma, D.</creator><creator>Demontiero, O.</creator><creator>Amiri, Z. Mohtasham</creator><creator>Hassan, S.</creator><creator>Suarez, H.</creator><creator>Geisinger, D.</creator><creator>Suriyaarachchi, P.</creator><creator>Sharma, A.</creator><creator>Duque, Gustavo</creator><general>Springer-Verlag</general><general>Springer</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20120301</creationdate><title>Vitamin D status in relation to postural stability in the elderly</title><author>Boersma, D. ; Demontiero, O. ; Amiri, Z. Mohtasham ; Hassan, S. ; Suarez, H. ; Geisinger, D. ; Suriyaarachchi, P. ; Sharma, A. ; Duque, Gustavo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c510t-f54757cdca0cf94964177ebfa163e57e59ed98af4a86ba6901f63bcea9814a9b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Accidental Falls - prevention & control</topic><topic>Accidental Falls - statistics & numerical data</topic><topic>Aged</topic><topic>Aging</topic><topic>Australia</topic><topic>Balance</topic><topic>Biological and medical sciences</topic><topic>Bones</topic><topic>Cross-Sectional Studies</topic><topic>Disease</topic><topic>Falls</topic><topic>Feeding. Feeding behavior</topic><topic>Female</topic><topic>Fractures</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Gait</topic><topic>Gait - physiology</topic><topic>Geriatric Assessment</topic><topic>Geriatrics</topic><topic>Geriatrics/Gerontology</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Motor Activity - physiology</topic><topic>Muscle Strength - physiology</topic><topic>Neurosciences</topic><topic>Nutrition</topic><topic>Nutrition Assessment</topic><topic>Nutritional Status</topic><topic>Older people</topic><topic>Parathyroid Hormone - blood</topic><topic>Parkinson's disease</topic><topic>Population</topic><topic>Posture</topic><topic>Posture - physiology</topic><topic>Primary Care Medicine</topic><topic>Quality of Life Research</topic><topic>Risk Factors</topic><topic>Vertebrates: anatomy and physiology, studies on body, several organs or systems</topic><topic>Vitamin D</topic><topic>Vitamin D - analogs & derivatives</topic><topic>Vitamin D - blood</topic><topic>Vitamin D Deficiency - blood</topic><topic>Vitamin D Deficiency - complications</topic><topic>Vitamin D Status in Relation to Postural Stability in the Elderly</topic><topic>Vitamin deficiency</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Boersma, D.</creatorcontrib><creatorcontrib>Demontiero, O.</creatorcontrib><creatorcontrib>Amiri, Z. Mohtasham</creatorcontrib><creatorcontrib>Hassan, S.</creatorcontrib><creatorcontrib>Suarez, H.</creatorcontrib><creatorcontrib>Geisinger, D.</creatorcontrib><creatorcontrib>Suriyaarachchi, P.</creatorcontrib><creatorcontrib>Sharma, A.</creatorcontrib><creatorcontrib>Duque, Gustavo</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of nutrition, health & aging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Boersma, D.</au><au>Demontiero, O.</au><au>Amiri, Z. Mohtasham</au><au>Hassan, S.</au><au>Suarez, H.</au><au>Geisinger, D.</au><au>Suriyaarachchi, P.</au><au>Sharma, A.</au><au>Duque, Gustavo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vitamin D status in relation to postural stability in the elderly</atitle><jtitle>The Journal of nutrition, health & aging</jtitle><stitle>J Nutr Health Aging</stitle><addtitle>J Nutr Health Aging</addtitle><date>2012-03-01</date><risdate>2012</risdate><volume>16</volume><issue>3</issue><spage>270</spage><epage>275</epage><pages>270-275</pages><issn>1279-7707</issn><eissn>1760-4788</eissn><abstract>Objectives
Postural instability (PI) is an important risk factor for falls, especially in the frail older population. In this study, we investigated the impact of vitamin D deficiency on PI in a sample of community dwelling older subjects. Our objective was to determine the potential association between vitamin D deficiency and PI in older fallers.
Design
Cross-sectional study.
Setting
Falls and Fractures Clinic, Department of Geriatric Medicine, Nepean Hospital, Penrith, Australia.
Participants
One hundred and forty-five adults aged 65 years and older who have had at least one episode of a fall within the six months prior to assessment at the Falls and Fractures Clinic.
Measurements
Serum 25(OH) vitamin D3 [25(OH)D3] and parathyroid hormone concentrations were determined at baseline. Subjects were separated into 3 groups based on serum 25(OH)D3 levels with the following cut-off values: < 30 nmol/L (deficient), 30–50 nmol/L (insufficient) and > 50 nmol/L (normal). Other baseline measurements included body mass index, mini-nutritional assessment, grip strength, serum calcium concentration and creatinine clearance, which were used as covariables. PI was assessed using a computerized virtual reality system (Medicaa, Uruguay). Measured parameters included limits of stability (LOS) and centre of pressure (COP) under eyes closed on foam (ECF) and visio-vestibular stimulation. The estimated swaying area, computed from the ellipse of confidence under eyes closed standing on foam (ECF), was also used as a PI parameter. Gait velocity (GV) was measured using a GaitRITE walkway system.
Results
Posture was impaired in vitamin D deficiency (<30 nmol/L) as indicated by lower LOS (90 +/− 18), higher ECF (25 +/− 10) and slower GV (55 +/− 7) as compared with the insufficient and normal groups. After adjustment for demographic, biochemical and anthropometric variables, vitamin D deficiency significantly correlated with low LOS and high COP under ECF.
Conclusion
Low levels of vitamin D were associated with PI. This association could also have an effect on slow GV and increased risk of falls. In conclusion, using an objective method to measure balance in older fallers we have identified a novel role of vitamin D in balance control. Prospective studies are required to confirm the effect of vitamin D on PI and elucidate the mechanisms of this association.</abstract><cop>Paris</cop><pub>Springer-Verlag</pub><pmid>22456785</pmid><doi>10.1007/s12603-011-0345-5</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Accidental Falls - prevention & control Accidental Falls - statistics & numerical data Aged Aging Australia Balance Biological and medical sciences Bones Cross-Sectional Studies Disease Falls Feeding. Feeding behavior Female Fractures Fundamental and applied biological sciences. Psychology Gait Gait - physiology Geriatric Assessment Geriatrics Geriatrics/Gerontology Hospitals Humans Male Medicine Medicine & Public Health Motor Activity - physiology Muscle Strength - physiology Neurosciences Nutrition Nutrition Assessment Nutritional Status Older people Parathyroid Hormone - blood Parkinson's disease Population Posture Posture - physiology Primary Care Medicine Quality of Life Research Risk Factors Vertebrates: anatomy and physiology, studies on body, several organs or systems Vitamin D Vitamin D - analogs & derivatives Vitamin D - blood Vitamin D Deficiency - blood Vitamin D Deficiency - complications Vitamin D Status in Relation to Postural Stability in the Elderly Vitamin deficiency |
title | Vitamin D status in relation to postural stability in the elderly |
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