Crescentic glomerulonephritis in IgA multiple myeloma: a case report

BACKGROUNDThere are few reports of glomerulonephritis (GN) with crescents and a rapidly progressive course that lead to a diagnosis of a previously unsuspected B-cell dyscrasia. CASE PRESENTATIONWe report a case of rapidly progressive GN: the patient showed no evidence of etiology at the time of bio...

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Bibliographic Details
Published in:Nephron extra 2011, Vol.1 (1), p.69-72
Main Authors: Moscoso-Solorzano, Grace T, Madureira-Silva, Marcus V, Balda, Carlos, Franco, Marcello F, Mastroianni-Kirsztajn, Gianna
Format: Report
Language:English
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Summary:BACKGROUNDThere are few reports of glomerulonephritis (GN) with crescents and a rapidly progressive course that lead to a diagnosis of a previously unsuspected B-cell dyscrasia. CASE PRESENTATIONWe report a case of rapidly progressive GN: the patient showed no evidence of etiology at the time of biopsy and was diagnosed as IgA multiple myeloma (MM) during investigation based on a renal biopsy. He presented diffuse proliferative and exudative GN and marked plasma cell infiltration of the kidney. CONCLUSIONThe present case raises the possibility that proliferative GN with crescents may be a rare mode of presentation of MM.
ISSN:1664-5529
DOI:10.1159/000331217