Public health impact of including two lineages of influenza B in a quadrivalent seasonal influenza vaccine

Highlights ► Estimated public health benefit of a quadrivalent vs. trivalent influenza vaccine. ► We calculated net impact on influenza-related illness, hospitalization, and death. ► We included data on vaccination and influenza outcomes from 1999 to 2009. ► Use of QIV could yield a modest reduction...

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Bibliographic Details
Published in:Vaccine 2012-03, Vol.30 (11), p.1993-1998
Main Authors: Reed, Carrie, Meltzer, Martin I, Finelli, Lyn, Fiore, Anthony
Format: Article
Language:English
Subjects:
Allergy and Immunology
Cross Protection
Data processing
death
Disease Outbreaks - prevention & control
Fatalities
Humans
Immunization
Influenza
Influenza A Virus, H1N1 Subtype - immunology
Influenza A Virus, H3N2 Subtype - immunology
Influenza B
Influenza B virus
Influenza B virus - classification
Influenza B virus - immunology
Influenza vaccine
Influenza Vaccines - administration & dosage
Influenza Vaccines - immunology
Influenza, Human - epidemiology
Influenza, Human - prevention & control
Models, Theoretical
prediction
Public Health
United States - epidemiology
Vaccination
Vaccines
viruses
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Summary:Highlights ► Estimated public health benefit of a quadrivalent vs. trivalent influenza vaccine. ► We calculated net impact on influenza-related illness, hospitalization, and death. ► We included data on vaccination and influenza outcomes from 1999 to 2009. ► Use of QIV could yield a modest reduction in illness, hospitalization, and death. ► Net impact varies by season, depending on the incidence of influenza B lineages.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2011.12.098