First case report of an acute genotype 3 hepatitis E infected pregnant woman living in South-Eastern France

Abstract In European countries, epidemiology of hepatitis E virus (HEV) infection is not well known. Although, seroprevalence of HEV Immunoglobulin G reached a few percent in European women, no acute hepatitis E during pregnancy has been described so far. Here, we report a case of an autochthonous H...

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Bibliographic Details
Published in:Journal of clinical virology 2012-05, Vol.54 (1), p.76-78
Main Authors: Anty, R, Ollier, L, Péron, J.M, Nicand, E, Cannavo, I, Bongain, A, Giordanengo, V, Tran, A
Format: Article
Language:English
Subjects:
Adult
Allergy and Immunology
Biological and medical sciences
Female
France
Fundamental and applied biological sciences. Psychology
Genotype
Genotype 3
Hepatitis E
Hepatitis E - diagnosis
Hepatitis E virus - classification
Hepatitis E virus - genetics
Hepatitis E virus - isolation & purification
Human viral diseases
Humans
Infant
Infant, Newborn
Infectious Disease
Infectious diseases
Medical sciences
Microbiology
Miscellaneous
Pregnancy
Pregnancy Complications, Infectious - diagnosis
RNA, Viral - genetics
Treatment Outcome
Viral diseases
Viral hepatitis
Virology
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Summary:Abstract In European countries, epidemiology of hepatitis E virus (HEV) infection is not well known. Although, seroprevalence of HEV Immunoglobulin G reached a few percent in European women, no acute hepatitis E during pregnancy has been described so far. Here, we report a case of an autochthonous HEV genotype 3 infection in a 41-years-old pregnant woman living in a non-endemic country. The acute hepatitis had a spontaneous good outcome for the mother and the child. In non-endemic areas where Hepatitis E infections are emerging, unexplained cytolysis, whatever its level, in a pregnant woman could be investigated for HEV, using biological molecular and serology tools.
ISSN:1386-6532
1873-5967
DOI:10.1016/j.jcv.2012.01.016