Polyclonal antibodies: a cheap and efficient tool for screening of enantioselective catalysts

Enantioselective polyclonal antibodies have been produced and characterized to develop a high-throughput screening method for lipase activity fingerprinting, with a view to the enantioselective hydrolysis of azlactones.

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2012-05, Vol.48 (37), p.4411-4413
Main Authors: Macovei, Cristian, Vicennati, Paola, Quinton, Julia, Nevers, Marie-Claire, Volland, Hervé, Créminon, Christophe, Taran, Frédéric
Format: Article
Language:English
Subjects:
Antibodies - immunology
Antibody Specificity
Catalysis
Drug Evaluation, Preclinical - economics
Drug Evaluation, Preclinical - methods
High-Throughput Screening Assays
Lactones - chemistry
Lipase - metabolism
Stereoisomerism
Water - chemistry
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Description
Summary:Enantioselective polyclonal antibodies have been produced and characterized to develop a high-throughput screening method for lipase activity fingerprinting, with a view to the enantioselective hydrolysis of azlactones.
ISSN:1359-7345
1364-548X
DOI:10.1039/c2cc31312j