Separations of intact IgGs using non-porous, 2 µm particle, C18 presto column, with a view towards ADC analysis

[...]since there are no pores, there is virtually no size limit for molecules that can be injected on the column. [...]small molecules can also be retained more efficiently on C18 and produce sharper elution peaks.

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Bibliographic Details
Published in:LC GC North America 2016-06, p.S30
Main Authors: Macech, Piotr, Puryear, Robert, Yazawa, Itaru, Usa, Imtakt
Format: Magazinearticle
Language:English
Subjects:
Antibodies
Chromatography
Proteins
Online Access:Get full text
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Description
Summary:[...]since there are no pores, there is virtually no size limit for molecules that can be injected on the column. [...]small molecules can also be retained more efficiently on C18 and produce sharper elution peaks.
ISSN:1527-5949
1939-1889