The use of topical ascorbyl palmitate and alpha lipoic acid for aging skin

Scientists have struggled for close to a century to understand the aging process, with little progress until Doctor Denham Harman proposed the free radical theory of aging in 1965. Harman explained that aging was the result of damage to cellular components by free radicals, predominately intermediat...

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Bibliographic Details
Published in:Global cosmetic industry 1998-02, Vol.162 (2), p.20
Main Author: Perricone, Nicholas V
Format: Magazinearticle
Language:English
Subjects:
Acids
Aging
Collagen
Cosmetics industry
Enzymes
Erythema
Fibroblasts
Free radicals
Inflammation
Lipids
Metabolism
R&D
Research & development
Skin
Statistical data
Ultraviolet radiation
Vitamin C
Vitamin E
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Summary:Scientists have struggled for close to a century to understand the aging process, with little progress until Doctor Denham Harman proposed the free radical theory of aging in 1965. Harman explained that aging was the result of damage to cellular components by free radicals, predominately intermediate oxygen species, which caused oxidation of proteins, lipids, cross-linking of proteins and damage to DNA. The chief defense against free radical damage is anti-oxidants. Anti-oxidants are molecules, many of them natural substances such vitamin C and vitamin E, that block the damaging reaction of reactive oxygen species. Use of topical anti-oxidants in the prevention and treatment of skin disease and aging has just begun.
ISSN:1523-9470