Effects of Natural and Pregelatinized Sorghum, Plantain, and Corn Starch Binders on the Compressional Characteristics of a Paracetamol Tablet Formulation

A study in which the comparative effects of natural and pregelatinized sorghum, plantain, and corn starch binders on the compressional characteristics of a paracetamol tablet formulation was made using density measurements and the Heckel and Kawakita plots for analysis. Results suggest that the use...

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Bibliographic Details
Published in:Pharmaceutical Technology North America 2001-09, Vol.25 (9), p.S26
Main Authors: Alebiowu, G, Itiola, O.A
Format: Magazinearticle
Language:English
Subjects:
Analgesics
Carbohydrates
Deformation
Density
Pharmaceutical industry
Pharmaceutical sciences
Pharmacy
R&D
Research & development
Sorghum
Statistical analysis
Studies
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Summary:A study in which the comparative effects of natural and pregelatinized sorghum, plantain, and corn starch binders on the compressional characteristics of a paracetamol tablet formulation was made using density measurements and the Heckel and Kawakita plots for analysis. Results suggest that the use of pregelatinized starches would improve the plastic deformation in the tablet formulations during compression when compared with the use of natural starches.
ISSN:1543-2521
2150-7376