Metal-Free Columns Significantly Improve Peak Shape, Recovery, and Sensitivity for Phosphorylated Compounds

Phosphorylated compounds readily adsorb to stainless steel surfaces present within the flow path of an HPLC system. This process can lead to poor peak shape, low recovery of sample, and reduction in sensitivity. Here we show that our metal-free column housing technology can improve analysis of these...

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Bibliographic Details
Published in:LC GC North America 2018-06, Vol.36 (6), p.421-421
Main Authors: Puryear, Robert, Macech, Piotr, Austin, Dustin, Yazawa, Itaru
Format: Magazinearticle
Language:English
Subjects:
Adsorption
Housing
Liquid chromatography
Metals
Recovery
Sensitivity
Stainless steel
Technology assessment
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Summary:Phosphorylated compounds readily adsorb to stainless steel surfaces present within the flow path of an HPLC system. This process can lead to poor peak shape, low recovery of sample, and reduction in sensitivity. Here we show that our metal-free column housing technology can improve analysis of these compounds.
ISSN:1527-5949
1939-1889