Nasal decolonization: potential mupirocin alternatives for SSI prevention

A consequence of mupirocin use, however, has been the development of mupirocin-resistant staphylococci. Because of concerns about resistance and whether patients can be relied upon to apply mupirocin before surgery, alternative approaches to nasal decolonization are being investigated. All participa...

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Bibliographic Details
Published in:Infectious Disease News 2019-07, Vol.32 (7), p.7-7
Main Author: Brock, Jeff
Format: Article
Language:English
Subjects:
Alcohol
Antimicrobial agents
Bone surgery
Iodine
Joint surgery
Patients
Staphylococcus infections
Studies
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Summary:A consequence of mupirocin use, however, has been the development of mupirocin-resistant staphylococci. Because of concerns about resistance and whether patients can be relied upon to apply mupirocin before surgery, alternative approaches to nasal decolonization are being investigated. All participants had a final nasal culture 6 weeks from completion of the initial treatment. Because of the low yield of mupirocin-resistant MRSA strains, recruitment was challenging in the trial. Because mupirocin resistance continues to increase worldwide, we will likely see additional trials with these agents, as well as studies of other novel agents in the future. ?
ISSN:1056-9251