Neoadjuvant Intralesional 5-Fluorouracil Injection

After discussing the options for treatment, including Mohs surgery with oculoplastic coordination, radiation, and intralesional chemotherapy, we decided together to do neoadjuvant intralesional 5-FU to decrease the size of the tumor and hopefully give her more time to make her final treatment decisi...

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Bibliographic Details
Published in:Dermatology Times 2024-10, Vol.45 (10), p.22-23
Main Author: Negbenebor, Nicole A
Format: Article
Language:English
Subjects:
Cancer surgery
Cancer therapies
Chemotherapy
Dementia
Dermatology
Patients
Radiation
Skin cancer
Squamous cell carcinoma
Online Access:Get full text
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Summary:After discussing the options for treatment, including Mohs surgery with oculoplastic coordination, radiation, and intralesional chemotherapy, we decided together to do neoadjuvant intralesional 5-FU to decrease the size of the tumor and hopefully give her more time to make her final treatment decision. There are many research studies with results demonstrating the efficacy of intralesional 5-FU for the treatment of patients with SCC. Older age or comorbidities For example, I had a patient in a nursing home who had a large SCC on the nose and opted for neoadjuvant intralesional 5-FU to minimize the possibility of requiring a large interpolation flap.
ISSN:0196-6197
2150-6523