Evaluation and characteristics of a new direct compression performance excipient

Performance excipients targeted for direct compression must provide high flowability, good compressibility under pressure, and excellent blend uniformity when mixed with active pharmaceutical ingrethents (APIs) or other ingrethents. The authors investigated the tableting properties of PanExcea MHC30...

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Bibliographic Details
Published in:Pharmaceutical Technology 2011-03, Vol.35 (3), p.98
Main Authors: Miinea, Liliana A, Mehta, Rajendra, Kallam, Madhu, Farina, James A, Deorkar, Nandu
Format: Magazinearticle
Language:English
Subjects:
Acids
Cellulose
Equipment and supplies
Evaluation
Granular materials
Industrial equipment
Manufacturing
Moisture content
Morphology
Nonsteroidal anti-inflammatory drugs
Pharmaceutical industry
Pharmaceuticals
Physical properties
Process controls
Production processes
Quality management
Specialty products
Studies
Tablets (Medicine)
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Summary:Performance excipients targeted for direct compression must provide high flowability, good compressibility under pressure, and excellent blend uniformity when mixed with active pharmaceutical ingrethents (APIs) or other ingrethents. The authors investigated the tableting properties of PanExcea MHC300G, a high-performance excipient with spherical particle morphology containing filler, binder, and disintegrant. [PUBLICATION ABSTRACT]
ISSN:1543-2521
2150-7376