Real-time monitoring of tablet film thickness in a fluid-bed coater using FT-NIR

Tablet coating thickness is a key parameter influencing the dissolution rate of drug in human body. Multiple variables may influence the quality and degree of coating; heat and mass transfer characteristics, coating curing, spray configuration, nature of me coating material, geometry of the system,...

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Bibliographic Details
Published in:Spectroscopy 2010-09, Vol.25 (9), p.SS15
Main Authors: Choi, Guang-Jin, Despagne, Frederic
Format: Magazinearticle
Language:English
Subjects:
Coatings
Fourier transforms
Infrared radiation
Spectrum analysis
Thin film coatings
Online Access:Get full text
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Summary:Tablet coating thickness is a key parameter influencing the dissolution rate of drug in human body. Multiple variables may influence the quality and degree of coating; heat and mass transfer characteristics, coating curing, spray configuration, nature of me coating material, geometry of the system, rate, and extent of coating accumulation.
ISSN:0887-6703
1939-1900